Ligand source activities (1 row/activity)
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
AssayType |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
1499 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
3779 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
536 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
CHEMBL434 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
DB01064 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
1499 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
3779 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
536 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
CHEMBL434 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
DB01064 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
1183 | 10743 | 0 | None | 1 | 3 | Human | 3.3 | pEC50 | = | 3.3 | Functional | Guide to Pharmacology | 152 | 2 | 1 | 3 | 1.2 | COc1cc(C=O)ccc1O | 34307435 | ||
6412 | 10743 | 0 | None | 1 | 3 | Human | 3.3 | pEC50 | = | 3.3 | Functional | Guide to Pharmacology | 152 | 2 | 1 | 3 | 1.2 | COc1cc(C=O)ccc1O | 34307435 | ||
CHEMBL13883 | 10743 | 0 | None | 1 | 3 | Human | 3.3 | pEC50 | = | 3.3 | Functional | Guide to Pharmacology | 152 | 2 | 1 | 3 | 1.2 | COc1cc(C=O)ccc1O | 34307435 | ||
10930 | 10612 | 0 | None | - | 1 | Human | 4.3 | pEC50 | = | 4.3 | Functional | Guide to Pharmacology | 467 | 6 | 10 | 14 | -6.3 | NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@H]([C@@H]([C@H]2O)O[C@H]2O[C@H](CO)[C@H]([C@@H]([C@H]2O)N)O)N)[C@@H](C[C@@H]1O)N | 30011231 | ||
2684 | 10612 | 0 | None | - | 1 | Human | 4.3 | pEC50 | = | 4.3 | Functional | Guide to Pharmacology | 467 | 6 | 10 | 14 | -6.3 | NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@H]([C@@H]([C@H]2O)O[C@H]2O[C@H](CO)[C@H]([C@@H]([C@H]2O)N)O)N)[C@@H](C[C@@H]1O)N | 30011231 | ||
36294 | 10612 | 0 | None | - | 1 | Human | 4.3 | pEC50 | = | 4.3 | Functional | Guide to Pharmacology | 467 | 6 | 10 | 14 | -6.3 | NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@H]([C@@H]([C@H]2O)O[C@H]2O[C@H](CO)[C@H]([C@@H]([C@H]2O)N)O)N)[C@@H](C[C@@H]1O)N | 30011231 | ||
CHEMBL1747 | 10612 | 0 | None | - | 1 | Human | 4.3 | pEC50 | = | 4.3 | Functional | Guide to Pharmacology | 467 | 6 | 10 | 14 | -6.3 | NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@H]([C@@H]([C@H]2O)O[C@H]2O[C@H](CO)[C@H]([C@@H]([C@H]2O)N)O)N)[C@@H](C[C@@H]1O)N | 30011231 | ||
DB00684 | 10612 | 0 | None | - | 1 | Human | 4.3 | pEC50 | = | 4.3 | Functional | Guide to Pharmacology | 467 | 6 | 10 | 14 | -6.3 | NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@H]([C@@H]([C@H]2O)O[C@H]2O[C@H](CO)[C@H]([C@@H]([C@H]2O)N)O)N)[C@@H](C[C@@H]1O)N | 30011231 | ||
2882 | 7991 | 62 | None | -588 | 5 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 468 | 8 | 3 | 9 | 2.1 | OC(COc1cccc2c1c(=O)cc(o2)C(=O)O)COc1cccc2c1c(=O)cc(o2)C(=O)O | 20022913 | ||
741 | 7991 | 62 | None | -588 | 5 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 468 | 8 | 3 | 9 | 2.1 | OC(COc1cccc2c1c(=O)cc(o2)C(=O)O)COc1cccc2c1c(=O)cc(o2)C(=O)O | 20022913 | ||
7608 | 7991 | 62 | None | -588 | 5 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 468 | 8 | 3 | 9 | 2.1 | OC(COc1cccc2c1c(=O)cc(o2)C(=O)O)COc1cccc2c1c(=O)cc(o2)C(=O)O | 20022913 | ||
CHEMBL428880 | 7991 | 62 | None | -588 | 5 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 468 | 8 | 3 | 9 | 2.1 | OC(COc1cccc2c1c(=O)cc(o2)C(=O)O)COc1cccc2c1c(=O)cc(o2)C(=O)O | 20022913 | ||
DB01003 | 7991 | 62 | None | -588 | 5 | Human | 4.4 | pEC50 | = | 4.4 | Functional | Guide to Pharmacology | 468 | 8 | 3 | 9 | 2.1 | OC(COc1cccc2c1c(=O)cc(o2)C(=O)O)COc1cccc2c1c(=O)cc(o2)C(=O)O | 20022913 | ||
12457 | 9283 | 123 | None | 3 | 2 | Human | 4.9 | pEC50 | = | 4.9 | Functional | Guide to Pharmacology | 216 | 1 | 0 | 4 | 2.5 | COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2 | 26501253 | ||
4114 | 9283 | 123 | None | 3 | 2 | Human | 4.9 | pEC50 | = | 4.9 | Functional | Guide to Pharmacology | 216 | 1 | 0 | 4 | 2.5 | COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2 | 26501253 | ||
CHEMBL416 | 9283 | 123 | None | 3 | 2 | Human | 4.9 | pEC50 | = | 4.9 | Functional | Guide to Pharmacology | 216 | 1 | 0 | 4 | 2.5 | COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2 | 26501253 | ||
DB00553 | 9283 | 123 | None | 3 | 2 | Human | 4.9 | pEC50 | = | 4.9 | Functional | Guide to Pharmacology | 216 | 1 | 0 | 4 | 2.5 | COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2 | 26501253 | ||
5074 | 10105 | 80 | None | -363 | 8 | Human | 5.2 | pEC50 | = | 5.2 | Functional | Guide to Pharmacology | 477 | 5 | 0 | 5 | 5.5 | Fc1ccc(cc1)C(=C1CCN(CC1)CCc1c(C)nc2n(c1=O)ccs2)c1ccc(cc1)F | 26501253 | ||
97 | 10105 | 80 | None | -363 | 8 | Human | 5.2 | pEC50 | = | 5.2 | Functional | Guide to Pharmacology | 477 | 5 | 0 | 5 | 5.5 | Fc1ccc(cc1)C(=C1CCN(CC1)CCc1c(C)nc2n(c1=O)ccs2)c1ccc(cc1)F | 26501253 | ||
CHEMBL267777 | 10105 | 80 | None | -363 | 8 | Human | 5.2 | pEC50 | = | 5.2 | Functional | Guide to Pharmacology | 477 | 5 | 0 | 5 | 5.5 | Fc1ccc(cc1)C(=C1CCN(CC1)CCc1c(C)nc2n(c1=O)ccs2)c1ccc(cc1)F | 26501253 | ||
DB12693 | 10105 | 80 | None | -363 | 8 | Human | 5.2 | pEC50 | = | 5.2 | Functional | Guide to Pharmacology | 477 | 5 | 0 | 5 | 5.5 | Fc1ccc(cc1)C(=C1CCN(CC1)CCc1c(C)nc2n(c1=O)ccs2)c1ccc(cc1)F | 26501253 |
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Similar- ity |
Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
Assay Type |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |