Ligand source activities (1 row/activity)
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| 68344426 | 175800 | None | 0 | Human | Functional | pEC50 | = | 4.5 | 4.5 | -4 | 3 | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R44 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level by FLIPR assayAgonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R44 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level by FLIPR assay |
ChEMBL | 250 | 0 | 1 | 3 | 2.6 | C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)C2CC1 | nan | ||
| CHEMBL4582048 | 175800 | None | 0 | Human | Functional | pEC50 | = | 4.5 | 4.5 | -4 | 3 | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R44 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level by FLIPR assayAgonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R44 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level by FLIPR assay |
ChEMBL | 250 | 0 | 1 | 3 | 2.6 | C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)C2CC1 | nan | ||
| 23259348 | 170016 | None | 0 | Human | Functional | pEC50 | = | 4.5 | 4.5 | -3 | 3 | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R44 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by FLIPR assayAgonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R44 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by FLIPR assay |
ChEMBL | 250 | 0 | 1 | 3 | 2.6 | C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)[C@@H]2CC1 | nan | ||
| CHEMBL4440983 | 170016 | None | 0 | Human | Functional | pEC50 | = | 4.5 | 4.5 | -3 | 3 | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R44 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by FLIPR assayAgonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R44 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by FLIPR assay |
ChEMBL | 250 | 0 | 1 | 3 | 2.6 | C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)[C@@H]2CC1 | nan | ||
| 1499 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.3 | 8.3 | -63 | 38 | Agonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| 3779 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.3 | 8.3 | -63 | 38 | Agonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| 3779.0 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.3 | 8.3 | -63 | 38 | Agonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| 536 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.3 | 8.3 | -63 | 38 | Agonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| CHEMBL434 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.3 | 8.3 | -63 | 38 | Agonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| DB01064 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.3 | 8.3 | -63 | 38 | Agonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| 1499 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.1 | 8.1 | -63 | 38 | Agonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| 3779 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.1 | 8.1 | -63 | 38 | Agonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| 3779.0 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.1 | 8.1 | -63 | 38 | Agonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| 536 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.1 | 8.1 | -63 | 38 | Agonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| CHEMBL434 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.1 | 8.1 | -63 | 38 | Agonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| DB01064 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.1 | 8.1 | -63 | 38 | Agonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R44 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| 12460 | 253 | None | 0 | Human | Functional | pEC50 | = | 2.6 | 2.6 | 1 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | 163 | 0 | 1 | 4 | -0.7 | CC1=CC(=O)NS(=O)(=O)O1 | 15537898 | ||
| 36573 | 253 | None | 0 | Human | Functional | pEC50 | = | 2.6 | 2.6 | 1 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | 163 | 0 | 1 | 4 | -0.7 | CC1=CC(=O)NS(=O)(=O)O1 | 15537898 | ||
| CHEMBL176687 | 253 | None | 0 | Human | Functional | pEC50 | = | 2.6 | 2.6 | 1 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | 163 | 0 | 1 | 4 | -0.7 | CC1=CC(=O)NS(=O)(=O)O1 | 15537898 | ||
| 5143 | 3457 | None | 0 | Human | Functional | pEC50 | = | 3.0 | 3.0 | 1 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | 183 | 0 | 1 | 3 | 0.1 | O=C1NS(=O)(=O)c2c1cccc2 | 15537898 | ||
| 5432 | 3457 | None | 0 | Human | Functional | pEC50 | = | 3.0 | 3.0 | 1 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | 183 | 0 | 1 | 3 | 0.1 | O=C1NS(=O)(=O)c2c1cccc2 | 15537898 | ||
| CHEMBL310671 | 3457 | None | 0 | Human | Functional | pEC50 | = | 3.0 | 3.0 | 1 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | 183 | 0 | 1 | 3 | 0.1 | O=C1NS(=O)(=O)c2c1cccc2 | 15537898 | ||
| 12438 | 471 | None | 0 | Human | Functional | pEC50 | = | 6.4 | 6.4 | -5 | 3 | UnclassifiedUnclassified |
Guide to Pharmacology | 341 | 3 | 1 | 6 | 3.3 | COC1=CC=CC2=C3C(=C(C=C21)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O | 15537898 | ||
| 2236 | 471 | None | 0 | Human | Functional | pEC50 | = | 6.4 | 6.4 | -5 | 3 | UnclassifiedUnclassified |
Guide to Pharmacology | 341 | 3 | 1 | 6 | 3.3 | COC1=CC=CC2=C3C(=C(C=C21)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O | 15537898 | ||
| CHEMBL93353 | 471 | None | 0 | Human | Functional | pEC50 | = | 6.4 | 6.4 | -5 | 3 | UnclassifiedUnclassified |
Guide to Pharmacology | 341 | 3 | 1 | 6 | 3.3 | COC1=CC=CC2=C3C(=C(C=C21)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O | 15537898 | ||
| 12470 | 1276 | None | 0 | Human | Functional | pIC50 | = | 1.8 | 1.8 | -3 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | 179 | 2 | 2 | 2 | 0.7 | C1CCC(CC1)NS(=O)(=O)O | 28919036 | ||
| 7533 | 1276 | None | 0 | Human | Functional | pIC50 | = | 1.8 | 1.8 | -3 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | 179 | 2 | 2 | 2 | 0.7 | C1CCC(CC1)NS(=O)(=O)O | 28919036 | ||
| CHEMBL1206440 | 1276 | None | 0 | Human | Functional | pIC50 | = | 1.8 | 1.8 | -3 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | 179 | 2 | 2 | 2 | 0.7 | C1CCC(CC1)NS(=O)(=O)O | 28919036 | ||
| 412 | 3460 | None | 34 | Human | Functional | pIC50 | = | 5.3 | 5.3 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 286 | 2 | 2 | 5 | 2.8 | COc1cc2O[C@@H](CC(=O)c2c(c1)O)c1ccc(cc1)O | 22059530 | ||
| 73571 | 3460 | None | 34 | Human | Functional | pIC50 | = | 5.3 | 5.3 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 286 | 2 | 2 | 5 | 2.8 | COc1cc2O[C@@H](CC(=O)c2c(c1)O)c1ccc(cc1)O | 22059530 | ||
| CHEMBL448297 | 3460 | None | 34 | Human | Functional | pIC50 | = | 5.3 | 5.3 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 286 | 2 | 2 | 5 | 2.8 | COc1cc2O[C@@H](CC(=O)c2c(c1)O)c1ccc(cc1)O | 22059530 | ||
| DB08517 | 3460 | None | 34 | Human | Functional | pIC50 | = | 5.3 | 5.3 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 286 | 2 | 2 | 5 | 2.8 | COc1cc2O[C@@H](CC(=O)c2c(c1)O)c1ccc(cc1)O | 22059530 | ||
| 25099817 | 1802 | None | 0 | Human | Functional | pIC50 | = | 5.5 | 5.5 | 1 | 3 | UnclassifiedUnclassified |
Guide to Pharmacology | 198 | 4 | 1 | 1 | 3.3 | CC1CCC(C1(C)C)CCCC(=O)O | 20537538 | ||
| 9112 | 1802 | None | 0 | Human | Functional | pIC50 | = | 5.5 | 5.5 | 1 | 3 | UnclassifiedUnclassified |
Guide to Pharmacology | 198 | 4 | 1 | 1 | 3.3 | CC1CCC(C1(C)C)CCCC(=O)O | 20537538 | ||
Showing 1 to 34 of 34 entries
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| 5379096 | 186513 | None | 55 | Human | Binding | pIC50 | = | 5.0 | 5.0 | - | 0 | Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunitInhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunit |
ChEMBL | 330 | 3 | 3 | 7 | 2.6 | COc1cc(-c2cc(=O)c3c(O)c(OC)c(O)cc3o2)ccc1O | 10.1021/np200391c | ||
| CHEMBL487601 | 186513 | None | 55 | Human | Binding | pIC50 | = | 5.0 | 5.0 | - | 0 | Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunitInhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunit |
ChEMBL | 330 | 3 | 3 | 7 | 2.6 | COc1cc(-c2cc(=O)c3c(O)c(OC)c(O)cc3o2)ccc1O | 10.1021/np200391c | ||
| 44576022 | 187048 | None | 1 | Human | Binding | pIC50 | = | 5.7 | 5.7 | - | 0 | Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunitInhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunit |
ChEMBL | 372 | 4 | 2 | 7 | 3.4 | COc1cc([C@@H]2CC(=O)c3c(O)cc(O)cc3O2)ccc1OC(=O)C(C)C | 10.1021/np200391c | ||
| CHEMBL490162 | 187048 | None | 1 | Human | Binding | pIC50 | = | 5.7 | 5.7 | - | 0 | Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunitInhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunit |
ChEMBL | 372 | 4 | 2 | 7 | 3.4 | COc1cc([C@@H]2CC(=O)c3c(O)cc(O)cc3O2)ccc1OC(=O)C(C)C | 10.1021/np200391c | ||
| 44412004 | 78290 | None | 0 | Human | Binding | pIC50 | = | 5.6 | 5.6 | - | 0 | Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunitInhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunit |
ChEMBL | 316 | 3 | 2 | 6 | 2.8 | COc1cc2c(c(O)c1OC)C(=O)C[C@@H](c1ccc(O)cc1)O2 | 10.1021/np200391c | ||
| CHEMBL210692 | 78290 | None | 0 | Human | Binding | pIC50 | = | 5.6 | 5.6 | - | 0 | Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunitInhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunit |
ChEMBL | 316 | 3 | 2 | 6 | 2.8 | COc1cc2c(c(O)c1OC)C(=O)C[C@@H](c1ccc(O)cc1)O2 | 10.1021/np200391c | ||
| 412 | 3460 | None | 34 | Human | Binding | pIC50 | = | 5.4 | 5.4 | - | 3 | Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunitInhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunit |
ChEMBL | 286 | 2 | 2 | 5 | 2.8 | COc1cc2O[C@@H](CC(=O)c2c(c1)O)c1ccc(cc1)O | 10.1021/np200391c | ||
| 73571 | 3460 | None | 34 | Human | Binding | pIC50 | = | 5.4 | 5.4 | - | 3 | Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunitInhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunit |
ChEMBL | 286 | 2 | 2 | 5 | 2.8 | COc1cc2O[C@@H](CC(=O)c2c(c1)O)c1ccc(cc1)O | 10.1021/np200391c | ||
| CHEMBL448297 | 3460 | None | 34 | Human | Binding | pIC50 | = | 5.4 | 5.4 | - | 3 | Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunitInhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunit |
ChEMBL | 286 | 2 | 2 | 5 | 2.8 | COc1cc2O[C@@H](CC(=O)c2c(c1)O)c1ccc(cc1)O | 10.1021/np200391c | ||
| DB08517 | 3460 | None | 34 | Human | Binding | pIC50 | = | 5.4 | 5.4 | - | 3 | Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunitInhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunit |
ChEMBL | 286 | 2 | 2 | 5 | 2.8 | COc1cc2O[C@@H](CC(=O)c2c(c1)O)c1ccc(cc1)O | 10.1021/np200391c | ||
| 13858192 | 113372 | None | 15 | Human | Binding | pIC50 | = | 5.1 | 5.1 | - | 0 | Antagonist activity at human TAS2R31 expressed in HEK-293T cells stably expressing Galpha16gust44 assessed as inhibition receptor response to saccharin by fluorescence assayAntagonist activity at human TAS2R31 expressed in HEK-293T cells stably expressing Galpha16gust44 assessed as inhibition receptor response to saccharin by fluorescence assay |
ChEMBL | 362 | 5 | 1 | 3 | 5.1 | C=C1CC[C@H]2C(C)(C)[C@@H](OC(C)=O)CC[C@]2(C)[C@H]1CC/C(C)=C/C(=O)O | 10.1021/np5001413 | ||
| CHEMBL3315351 | 113372 | None | 15 | Human | Binding | pIC50 | = | 5.1 | 5.1 | - | 0 | Antagonist activity at human TAS2R31 expressed in HEK-293T cells stably expressing Galpha16gust44 assessed as inhibition receptor response to saccharin by fluorescence assayAntagonist activity at human TAS2R31 expressed in HEK-293T cells stably expressing Galpha16gust44 assessed as inhibition receptor response to saccharin by fluorescence assay |
ChEMBL | 362 | 5 | 1 | 3 | 5.1 | C=C1CC[C@H]2C(C)(C)[C@@H](OC(C)=O)CC[C@]2(C)[C@H]1CC/C(C)=C/C(=O)O | 10.1021/np5001413 | ||
Showing 1 to 12 of 12 entries