Ligand source activities (1 row/activity)





Ligands (move mouse cursor over ligand name to see structure) Receptor Assay information Chemical information
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1499 8872 47 None -63 38 Human 8.3 pEC50 = 8.3 Functional
Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
3779 8872 47 None -63 38 Human 8.3 pEC50 = 8.3 Functional
Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
536 8872 47 None -63 38 Human 8.3 pEC50 = 8.3 Functional
Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
CHEMBL434 8872 47 None -63 38 Human 8.3 pEC50 = 8.3 Functional
Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
DB01064 8872 47 None -63 38 Human 8.3 pEC50 = 8.3 Functional
Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
1499 8872 47 None -63 38 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Drug Central 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C None
3779 8872 47 None -63 38 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Drug Central 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C None
536 8872 47 None -63 38 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Drug Central 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C None
CHEMBL434 8872 47 None -63 38 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Drug Central 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C None
DB01064 8872 47 None -63 38 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Drug Central 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C None
1183 10743 0 None -1 3 Human 3.1 pEC50 = 3.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology 152 2 1 3 1.2 COc1cc(C=O)ccc1O 34307435
6412 10743 0 None -1 3 Human 3.1 pEC50 = 3.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology 152 2 1 3 1.2 COc1cc(C=O)ccc1O 34307435
CHEMBL13883 10743 0 None -1 3 Human 3.1 pEC50 = 3.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology 152 2 1 3 1.2 COc1cc(C=O)ccc1O 34307435
12497 8353 101 None -13 2 Human 3.4 pEC50 = 3.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 290 1 5 6 1.5 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O 21272567
72276 8353 101 None -13 2 Human 3.4 pEC50 = 3.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 290 1 5 6 1.5 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O 21272567
CHEMBL583912 8353 101 None -13 2 Human 3.4 pEC50 = 3.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 290 1 5 6 1.5 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O 21272567
DB12039 8353 101 None -13 2 Human 3.4 pEC50 = 3.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 290 1 5 6 1.5 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O 21272567
12461 8355 82 None - 1 Human 3.4 pEC50 = 3.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 306 1 6 7 1.3 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O 21272567
72277 8355 82 None - 1 Human 3.4 pEC50 = 3.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 306 1 6 7 1.3 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O 21272567
CHEMBL47386 8355 82 None - 1 Human 3.4 pEC50 = 3.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 306 1 6 7 1.3 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O 21272567
DB03823 8355 82 None - 1 Human 3.4 pEC50 = 3.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 306 1 6 7 1.3 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O 21272567
12441 9914 0 None -1 2 Human 4.3 pEC50 = 4.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 242 1 2 3 2.8 C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O 21942422
382975 9914 0 None -1 2 Human 4.3 pEC50 = 4.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 242 1 2 3 2.8 C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O 21942422
CHEMBL1957037 9914 0 None -1 2 Human 4.3 pEC50 = 4.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 242 1 2 3 2.8 C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O 21942422
2826 8565 137 None -48 7 Human 4.3 pEC50 = 4.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 270 1 3 5 2.6 Oc1ccc(cc1)c1coc2c(c1=O)c(O)cc(c2)O 21942422
5280961 8565 137 None -48 7 Human 4.3 pEC50 = 4.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 270 1 3 5 2.6 Oc1ccc(cc1)c1coc2c(c1=O)c(O)cc(c2)O 21942422
CHEMBL44 8565 137 None -48 7 Human 4.3 pEC50 = 4.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 270 1 3 5 2.6 Oc1ccc(cc1)c1coc2c(c1=O)c(O)cc(c2)O 21942422
DB01645 8565 137 None -48 7 Human 4.3 pEC50 = 4.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 270 1 3 5 2.6 Oc1ccc(cc1)c1coc2c(c1=O)c(O)cc(c2)O 21942422
12440 8108 0 None -4 2 Human 4.4 pEC50 = 4.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 286 1 4 6 2.3 C1=CC=C(C(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O 24117141
5281610 8108 0 None -4 2 Human 4.4 pEC50 = 4.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 286 1 4 6 2.3 C1=CC=C(C(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O 24117141
CHEMBL503168 8108 0 None -4 2 Human 4.4 pEC50 = 4.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 286 1 4 6 2.3 C1=CC=C(C(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O 24117141
4285 9884 122 None -2 3 Human 4.4 pEC50 = 4.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 274 4 4 5 2.3 Oc1ccc(cc1)CCC(=O)c1c(O)cc(cc1O)O 24117141
4788 9884 122 None -2 3 Human 4.4 pEC50 = 4.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 274 4 4 5 2.3 Oc1ccc(cc1)CCC(=O)c1c(O)cc(cc1O)O 24117141
CHEMBL45068 9884 122 None -2 3 Human 4.4 pEC50 = 4.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 274 4 4 5 2.3 Oc1ccc(cc1)CCC(=O)c1c(O)cc(cc1O)O 24117141
DB07810 9884 122 None -2 3 Human 4.4 pEC50 = 4.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 274 4 4 5 2.3 Oc1ccc(cc1)CCC(=O)c1c(O)cc(cc1O)O 24117141
12463 10336 0 None - 1 Human 4.4 pEC50 = 4.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 286 1 4 6 2.3 C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O)O 24117141
5281697 10336 0 None - 1 Human 4.4 pEC50 = 4.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 286 1 4 6 2.3 C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O)O 24117141
CHEMBL55415 10336 0 None - 1 Human 4.4 pEC50 = 4.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology 286 1 4 6 2.3 C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O)O 24117141
10298 9513 0 None - 1 Human 4.5 pEC50 = 4.5 Functional
UnclassifiedUnclassified
Guide to Pharmacology 272 1 3 5 2.5 Oc1ccc(cc1)C1CC(=O)c2c(O1)cc(cc2O)O 24117141
932 9513 0 None - 1 Human 4.5 pEC50 = 4.5 Functional
UnclassifiedUnclassified
Guide to Pharmacology 272 1 3 5 2.5 Oc1ccc(cc1)C1CC(=O)c2c(O1)cc(cc2O)O 24117141
CHEMBL32571 9513 0 None - 1 Human 4.5 pEC50 = 4.5 Functional
UnclassifiedUnclassified
Guide to Pharmacology 272 1 3 5 2.5 Oc1ccc(cc1)C1CC(=O)c2c(O1)cc(cc2O)O 24117141
107905 8354 83 None - 1 Human 4.7 pEC50 = 4.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 442 3 7 10 2.5 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O 25273142
12462 8354 83 None - 1 Human 4.7 pEC50 = 4.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 442 3 7 10 2.5 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O 25273142
CHEMBL36327 8354 83 None - 1 Human 4.7 pEC50 = 4.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 442 3 7 10 2.5 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O 25273142
5215 9165 132 None -1 4 Human 5.1 pEC50 = 5.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology 286 1 4 6 2.3 Oc1cc(O)c2c(c1)oc(cc2=O)c1ccc(c(c1)O)O 24117141
5280445 9165 132 None -1 4 Human 5.1 pEC50 = 5.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology 286 1 4 6 2.3 Oc1cc(O)c2c(c1)oc(cc2=O)c1ccc(c(c1)O)O 24117141
CHEMBL151 9165 132 None -1 4 Human 5.1 pEC50 = 5.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology 286 1 4 6 2.3 Oc1cc(O)c2c(c1)oc(cc2=O)c1ccc(c(c1)O)O 24117141
12464 10569 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
UnclassifiedUnclassified
Guide to Pharmacology 564 2 9 12 2.2 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC4=C(C(=C(C=C4[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)O)O)O)C(=O)C(=C3)O)O 25273142
135403798 10569 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
UnclassifiedUnclassified
Guide to Pharmacology 564 2 9 12 2.2 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC4=C(C(=C(C=C4[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)O)O)O)C(=O)C(=C3)O)O 25273142
12465 10570 0 None - 1 Human 6.2 pEC50 = 6.2 Functional
UnclassifiedUnclassified
Guide to Pharmacology 716 4 11 16 3.2 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C4=C3C=C(C=C(C4=O)O)[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)OC(=O)C7=CC(=C(C(=C7)O)O)O)O)O)O 25273142
135458101 10570 0 None - 1 Human 6.2 pEC50 = 6.2 Functional
UnclassifiedUnclassified
Guide to Pharmacology 716 4 11 16 3.2 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C4=C3C=C(C=C(C4=O)O)[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)OC(=O)C7=CC(=C(C(=C7)O)O)O)O)O)O 25273142
12466 6951 0 None - 1 Human 4.7 pIC50 = 4.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 236 1 0 2 3.8 CC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3 24722342
689013 6951 0 None - 1 Human 4.7 pIC50 = 4.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 236 1 0 2 3.8 CC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3 24722342
CHEMBL134291 6951 0 None - 1 Human 4.7 pIC50 = 4.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 236 1 0 2 3.8 CC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3 24722342




Ligands (move mouse cursor over ligand name to see structure) Receptor Assay information Chemical information
Sel. page Similar-
ity
Common
name
GPCRdb
ID
#Vendors

Reference
ligand
Fold
selectivity
# Tested
GPCRs
Species

p-value
(-log)
Activity
Type
Activity
Relation
Activity
Value
Assay
Type
Assay
Description
Source

Mol
weight
Rot
Bonds
H don

H acc

LogP

Smiles

DOI