OR2B6 (or2b6_mouse)

FAMILY

Class O2 (tetrapod specific odorant) Odorant receptors Odorant family 2 OR2B6

GENE

Or2b6 (Mor256-11, Olfr11)

ORGANISM

Mouse (Mus musculus)

ALT. NAMES

Olfactory receptor 2B6, Odorant receptor M49, Olfactory receptor 11, Olfactory receptor 256-11

SOURCE

SWISSPROT

SEQUENCE

N-term        
M
S
W
A
N
E
S
I
T
G
10
                   
E
F
V
L
L
G
F
S
D
Q
20
TM1              
P
W
L
E
F
P
L
F
V
V
30
                   
F
L
T
S
Y
I
V
T
I
F
40
                   
G
N
L
N
I
I
L
V
S
H
50
    ICL1 TM2  
L
D
P
K
L
H
T
P
M
Y
60
                   
F
F
L
T
N
L
S
V
I
D
70
                   
L
C
Y
I
T
C
T
V
P
Q
80
                   
M
L
V
N
L
R
S
I
R
K
90
ECL1 TM3      
V
I
S
F
G
G
C
V
V
Q
100
                   
L
F
M
F
L
A
L
G
A
T
110
                   
E
C
V
L
L
P
V
M
S
F
120
                   
D
R
F
V
A
I
C
R
P
L
130
ICL2     TM4  
H
Y
S
V
I
M
H
Q
R
L
140
                   
C
L
Q
L
A
A
V
S
W
I
150
                   
I
G
F
G
N
S
V
W
L
S
160
          ECL2  
I
L
T
L
Q
L
P
R
C
G
170
                   
H
Y
V
I
D
H
F
L
C
E
180
                   
V
P
A
L
L
K
L
S
C
V
190
  TM5            
D
V
T
A
N
E
A
E
L
F
200
                   
F
V
S
V
F
F
H
L
T
P
210
                   
L
S
L
I
L
T
S
Y
A
F
220
            ICL3
I
A
R
A
I
L
K
I
Q
S
230
TM6              
A
E
G
R
Q
K
A
F
G
T
240
                   
C
S
S
H
L
I
V
V
S
L
250
                   
F
Y
G
T
A
L
S
V
Y
F
260
ECL3 TM7      
L
P
P
S
P
H
S
K
N
R
270
                   
R
K
M
V
P
L
F
Y
G
I
280
                   
I
A
P
M
L
N
P
L
I
Y
290
      H8          
T
L
R
N
K
E
V
K
D
A
300
                   
F
K
R
L
I
K
R
V
F
L
310
    C-term
S
K
N

LINKS

UniProt

DIAGRAMS

7TM

ICL1 P K L H ICL1ECL1 I R K V I ECL1ICL2 P L H Y S V I M ICL2ECL2 L P R C G H Y V I D H F L C E V P A L L K L S C V D ECL2ICL3 K I Q ICL3ECL3 L P P ECL3N-term M S W A N E S I T G E F V L L G F S D N-termC-term N C-term Q P W L E F P L F V V F L T S Y I V T I F G N L N I I L V S H L D T P M Y F F L T N L S V I D L C Y I T C T V P Q M L V N L R S S F G G C V V Q L F M F L A L G A T E C V L L P V M S F D R F V A I C R H Q R L C L Q L A A V S W I I G F G N S V W L S I L T L Q V T A N E A E L F F V S V F F H L T P L S L I L T S Y A F I A R A I L S A E G R Q K A F G T C S S H L I V V S L F Y G T A L S V Y F S P H S K N R R K M V P L F Y G I I A P M L N P L I Y T L R N K E F K R V F L V K D A L I K R S K
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

L N G F I T V I Y S T L F V V F L P F E 1 T N L S V I D L C Y I T C T V P Q M L V 2 V P L L V C E T A G L A L F M F L Q V V 3 C L Q L A A V S W I I G F G N S V W L S 4 Y S T L I L S L P T L H F F V S V F F L 5 S S H L I V V S L F Y G T A L S V Y F 6 L P N L M P A I I G Y F L P V M K R R 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available