GPR17 (gpr17_mouse)
FAMILY
Class A (Rhodopsin) Orphan receptors Class A orphans GPR17
GENE
Gpr17
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
Uracil nucleotide/cysteinyl leukotriene receptor, UDP/CysLT receptor, G-protein coupled receptor 17
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
N
|
G
|
L
|
E
|
A
|
A
|
L
|
P
|
S
|
10 |
L
|
T
|
D
|
N
|
S
|
S
|
L
|
A
|
Y
|
S
|
20 |
TM1 | |||||||||
E
|
Q
|
C
|
G
|
Q
|
E
|
T
|
P
|
L
|
E
|
30 |
N
|
M
|
L
|
F
|
A
|
C
|
F
|
Y
|
L
|
L
|
40 |
D
|
F
|
I
|
L
|
A
|
F
|
V
|
G
|
N
|
A
|
50 |
L
|
A
|
L
|
W
|
L
|
F
|
I
|
W
|
D
|
H
|
60 |
ICL1 | TM2 | ||||||||
K
|
S
|
G
|
T
|
P
|
A
|
N
|
V
|
F
|
L
|
70 |
M
|
H
|
L
|
A
|
V
|
A
|
D
|
L
|
S
|
C
|
80 |
V
|
L
|
V
|
L
|
P
|
T
|
R
|
L
|
V
|
Y
|
90 |
ECL1 | |||||||||
H
|
F
|
S
|
G
|
N
|
H
|
W
|
P
|
F
|
G
|
100 |
TM3 | |||||||||
E
|
I
|
P
|
C
|
R
|
L
|
T
|
G
|
F
|
L
|
110 |
F
|
Y
|
L
|
N
|
M
|
Y
|
A
|
S
|
I
|
Y
|
120 |
F
|
L
|
T
|
C
|
I
|
S
|
A
|
D
|
R
|
F
|
130 |
ICL2 | |||||||||
L
|
A
|
I
|
V
|
H
|
P
|
V
|
K
|
S
|
L
|
140 |
TM4 | |||||||||
K
|
L
|
R
|
R
|
P
|
L
|
Y
|
A
|
H
|
L
|
150 |
A
|
C
|
A
|
F
|
L
|
W
|
I
|
V
|
V
|
A
|
160 |
V
|
A
|
M
|
A
|
P
|
L
|
L
|
V
|
S
|
P
|
170 |
ECL2 | |||||||||
Q
|
T
|
V
|
Q
|
T
|
N
|
H
|
T
|
V
|
V
|
180 |
TM5 | |||||||||
C
|
L
|
Q
|
L
|
Y
|
R
|
E
|
K
|
A
|
S
|
190 |
H
|
H
|
A
|
L
|
A
|
S
|
L
|
A
|
V
|
A
|
200 |
F
|
T
|
F
|
P
|
F
|
I
|
T
|
T
|
V
|
T
|
210 |
C
|
Y
|
L
|
L
|
I
|
I
|
R
|
S
|
L
|
R
|
220 |
ICL3 | TM6 | ||||||||
Q
|
G
|
P
|
R
|
I
|
E
|
K
|
H
|
L
|
K
|
230 |
N
|
K
|
A
|
V
|
R
|
M
|
I
|
A
|
M
|
V
|
240 |
L
|
A
|
I
|
F
|
L
|
I
|
C
|
F
|
V
|
P
|
250 |
Y
|
H
|
I
|
H
|
R
|
S
|
V
|
Y
|
V
|
L
|
260 |
ECL3 | TM7 | |||||||||
H
|
Y
|
R
|
G
|
G
|
G
|
T
|
S
|
C
|
A
|
|
270 |
A
|
Q
|
R
|
A
|
L
|
A
|
L
|
G
|
N
|
R
|
280 |
I
|
T
|
S
|
C
|
L
|
T
|
S
|
L
|
N
|
G
|
290 |
A
|
L
|
D
|
P
|
V
|
M
|
Y
|
F
|
F
|
V
|
300 |
H8 | |||||||||
A
|
E
|
K
|
F
|
R
|
H
|
A
|
L
|
C
|
N
|
310 |
C-term | |||||||||
L
|
L
|
C
|
S
|
K
|
R
|
L
|
T
|
G
|
P
|
320 |
P
|
P
|
S
|
F
|
E
|
G
|
K
|
T
|
N
|
E
|
330 |
S
|
S
|
L
|
S
|
A
|
R
|
S
|
E
|
L
|
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
LTD4, UDP-galactose, LTC4, UDP-glucose, LTE4
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available