TAS2R1 (tr119_rat)

FAMILY

Class T2 (Taste 2) Sensory receptors Taste 2 receptors TAS2R1

GENE

Tas2r119 (Tas2r1, Tas2r19)

ORGANISM

Rat (Rattus norvegicus)

ALT. NAMES

Taste receptor type 2 member 119, T2R119, Taste receptor type 2 member 1, T2R1, Taste receptor type 2 member 19, T2R19

SOURCE

SWISSPROT

SEQUENCE

N-term TM1  
M
M
E
G
H
I
L
F
F
F
10
                   
L
V
V
M
V
Q
F
V
T
G
20
                   
V
L
A
N
G
L
I
V
V
V
30
                   
H
A
I
D
L
I
M
W
K
K
40
ICL1 TM2      
M
A
P
L
D
L
L
L
F
C
50
                   
L
A
T
S
R
I
I
L
Q
L
60
                   
C
I
L
F
A
Q
L
C
L
F
70
    ECL1 TM3  
S
L
V
R
H
T
L
F
E
D
80
                   
N
I
T
F
V
F
I
I
N
E
90
                   
L
S
L
W
F
A
T
W
L
G
100
                   
V
F
Y
C
A
K
I
A
T
I
110
ICL2            
P
H
P
L
F
L
W
L
K
M
120
TM4              
R
I
S
R
L
V
P
W
L
I
130
                   
L
G
S
V
L
Y
V
I
I
T
140
                   
T
F
I
H
S
R
E
T
S
A
150
ECL2            
I
L
K
P
I
F
I
S
L
F
160
                   
P
K
N
A
T
Q
V
G
T
G
170
      TM5        
H
A
T
L
L
S
V
L
V
L
180
                   
G
L
T
L
P
L
F
I
F
T
190
                   
V
A
V
L
L
L
I
Y
S
L
200
                   
W
N
Y
S
R
Q
M
R
T
M
210
  ICL3 TM6    
V
G
T
R
E
Y
S
G
H
A
220
                   
H
I
S
A
M
L
S
I
L
S
230
                   
F
L
I
L
Y
L
S
H
Y
M
240
                   
V
A
V
L
I
S
T
Q
V
L
250
  ECL3 TM7    
Y
L
G
S
R
T
F
V
F
C
260
                   
L
L
V
I
G
M
Y
P
S
I
270
                H8
H
S
I
V
L
I
L
G
N
P
280
                   
K
L
K
R
N
A
K
M
F
I
290
                   
V
H
C
K
C
C
H
C
T
R
300
C-term        
A
W
V
T
S
R
S
P
R
L
310
                   
S
D
L
P
V
P
P
T
H
P
320
                   
S
A
N
K
T
S
C
S
E
A
330
         
C
I
M
P
S

LINKS

UniProt

DIAGRAMS

7TM

ICL1 K M ICL1ECL1 V R H T ECL1ICL2 T I P H P L F L W L K M ICL2ECL2 A I L K P I F I S L F P K N A T Q V G T G H A T ECL2ICL3 G T R ICL3ECL3 L G ECL3N-term M N-termC-term C T R A W V T S R S P R L S D L P V P P T H P S A N K T S C S E A C I M P S C-term M E G H I L F F F L V V M V Q F V T G V L A N G L I V V V H A I D L I M W K A P L D L L L F C L A T S R I I L Q L C I L F A Q L C L F S L L F E D N I T F V F I I N E L S L W F A T W L G V F Y C A K I A R I S R L V P W L I L G S V L Y V I I T T F I H S R E T S L L S V L V L G L T L P L F I F T V A V L L L I Y S L W N Y S R Q M R T M V E Y S G H A H I S A M L S I L S F L I L Y L S H Y M V A V L I S T Q V L Y S R T F V F C L L V I G M Y P S I H S I V L I L G N P K A K M C K C L K R N F I V H C H
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

G N A L V G T V F Q V M V V L F F F L I 1 F C L A T S R I I L Q L C I L F A Q L C 2 W T A F W L S L E N I I F V F T I N D E 3 V P W L I L G S V L Y V I I T T F I H S 4 V A V T F I F L P L T L G L V L V S L L 5 I L S F L I L Y L S H Y M V A V L I S T 6 I S H I S P Y M G I V L L C F V F T R 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available