TAS2R14 (a0a0n9nvu2_nanga)

FAMILY

Class T2 (Taste 2) Sensory receptors Taste 2 receptors TAS2R14

GENE

Tas2r14 (Tas2r4)

ORGANISM

Northern Israeli blind subterranean mole rat (Nannospalax galili)

ALT. NAMES

Taste receptor type 2

SOURCE

TREMBL

SEQUENCE

TM1              
M
F
Q
E
L
N
L
F
V
F
10
                   
A
A
S
V
V
F
N
F
V
G
20
                   
L
I
V
S
L
F
I
I
V
V
30
                   
I
Y
K
T
W
V
R
S
R
R
40
ICL1 TM2      
L
S
S
S
D
R
I
L
F
S
50
                   
L
G
V
T
R
F
L
T
L
V
60
                   
L
F
L
L
K
T
V
Y
L
S
70
    ECL1 TM3  
S
N
G
K
K
S
V
Y
F
S
80
                   
M
A
F
V
F
C
W
K
F
L
90
                   
D
S
N
S
L
W
L
V
T
L
100
                   
L
N
S
L
Y
C
V
K
I
T
110
ICL2            
N
F
Q
H
P
M
F
L
L
L
120
            TM4  
K
R
N
I
S
A
K
T
T
R
130
                   
M
L
L
A
C
L
L
I
S
A
140
                   
F
T
T
L
L
Y
L
V
L
S
150
          ECL2  
Q
V
S
R
F
P
E
H
M
T
160
                   
G
R
N
D
T
V
F
D
F
S
170
          TM5    
E
G
I
L
I
L
A
A
S
L
180
                   
A
L
S
S
L
F
Q
F
V
L
190
                   
N
V
T
F
A
S
V
L
I
H
200
                   
S
L
R
R
H
I
Q
R
M
Q
210
      ICL3      
R
N
S
T
G
F
W
N
P
Q
220
        TM6      
T
E
A
H
L
G
A
V
K
L
230
                   
M
T
C
F
L
L
L
Y
I
P
240
                   
Y
S
V
A
T
L
F
Y
L
P
250
          ECL3 TM7
S
S
G
K
D
L
R
A
Y
A
260
               
V
C
V
I
I
T
A
A
Y
P
270
                   
P
G
H
S
V
L
I
I
F
T
280
H8                
H
S
K
L
K
T
K
A
K
K
290
           
I
L
R
F
Y
K

LINKS

UniProt

DIAGRAMS

7TM

ICL1 R R L ICL1ECL1 G K K ECL1ICL2 N F Q H P M F L L L K R N I S A ICL2ECL2 P E H M T G R N D T V F D F S E G I L I ECL2ICL3 T G F W N P Q T E A H ICL3ECL3 L ECL3 M F Q E L N L F V F A A S V V F N F V G L I V S L F I I V V I Y K T W V R S S S S D R I L F S L G V T R F L T L V L F L L K T V Y L S S N S V Y F S M A F V F C W K F L D S N S L W L V T L L N S L Y C V K I T K T T R M L L A C L L I S A F T T L L Y L V L S Q V S R F L A A S L A L S S L F Q F V L N V T F A S V L I H S L R R H I Q R M Q R N S L G A V K L M T C F L L L Y I P Y S V A T L F Y L P S S G K D R A Y A V C V I I T A A Y P P G H S V L I I F T H S K A K K Y K L K T K I L R F
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

L S V I L G V F N F V V S A A F V F L N 1 F S L G V T R F L T L V L F L L K T V Y 2 L T V L W L S N S D L F K W C F V F A M 3 L L A C L L I S A F T T L L Y L V L S Q 4 A F T V N L V F Q F L S S L A L S A A L 5 M T C F L L L Y I P Y S V A T L F Y L P 6 V S H G P P Y A A T I I V C V A Y A R 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available