TAS2R14 (a0a6j3fx25_sapap)

FAMILY

Class T2 (Taste 2) Sensory receptors Taste 2 receptors TAS2R14

GENE

TAS2R14

ORGANISM

Brown-capped capuchin (Sapajus apella)

ALT. NAMES

Taste receptor type 2

SOURCE

TREMBL

SEQUENCE

TM1              
M
S
G
V
I
K
S
I
L
T
10
                   
F
I
F
I
V
E
F
I
I
G
20
                   
N
L
G
N
G
F
I
A
L
V
30
                   
N
C
I
N
W
V
K
R
R
K
40
ICL1 TM2      
I
A
L
A
D
Q
I
L
T
A
50
                   
L
A
I
S
R
T
G
L
V
W
60
                   
L
I
F
V
S
W
Y
V
S
V
70
    ECL1   TM3
L
H
P
A
L
F
L
T
E
K
80
                   
M
L
R
M
F
I
N
T
W
V
90
                   
V
T
N
H
F
S
V
W
F
A
100
                   
A
S
L
S
T
F
Y
F
F
K
110
    ICL2        
I
A
N
F
S
N
S
I
F
L
120
        TM4      
Y
L
K
W
K
V
K
K
A
V
130
                   
L
V
L
L
L
V
T
L
V
L
140
                   
L
F
L
N
I
A
L
I
N
V
150
      ECL2      
H
I
N
A
R
I
N
E
D
S
160
                   
G
N
R
T
C
S
S
G
P
N
170
                   
N
F
A
Q
F
S
S
P
V
L
180
TM5              
L
T
S
T
V
F
F
L
I
P
190
                   
F
T
L
S
L
A
N
F
L
L
200
                   
L
T
F
S
L
W
K
H
V
K
210
            ICL3
K
M
H
H
T
V
K
G
S
G
220
              TM6
D
A
S
T
K
A
H
R
K
V
230
                   
I
Q
I
V
I
T
S
L
L
L
240
                   
Y
A
I
F
S
V
S
F
F
L
250
                   
P
L
W
I
S
E
L
L
E
E
260
ECL3 TM7      
N
L
I
F
I
F
C
Q
V
L
270
                   
T
M
S
Y
P
S
G
Q
S
C
280
          H8      
V
L
I
L
G
N
K
K
L
R
290
                   
Q
A
F
L
S
V
P
R
W
L
300
                   
T
C
R
F
K
D
G
E
P
S
310
C-term      
G
H
R
E
F
R
E
S
S

LINKS

UniProt

DIAGRAMS

7TM

ICL1 R K I ICL1ECL1 P A L F L ECL1ICL2 N F S N S I F L Y L K W ICL2ECL2 A R I N E D S G N R T C S S G P N N F A Q F S S P ECL2ICL3 K G S G D A S T K A H ICL3ECL3 E E N ECL3C-term G E P S G H R E F R E S S C-term M S G V I K S I L T F I F I V E F I I G N L G N G F I A L V N C I N W V K R A L A D Q I L T A L A I S R T G L V W L I F V S W Y V S V L H T E K M L R M F I N T W V V T N H F S V W F A A S L S T F Y F F K I A K V K K A V L V L L L V T L V L L F L N I A L I N V H I N V L L T S T V F F L I P F T L S L A N F L L L T F S L W K H V K K M H H T V R K V I Q I V I T S L L L Y A I F S V S F F L P L W I S E L L L I F I F C Q V L T M S Y P S G Q S C V L I L G N K K F L S L T C L R Q A V P R W R F K D
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

G N G L N G I I F E V I F I F T L I S K 1 T A L A I S R T G L V W L I F V S W Y V 2 S A A F W V S F H N T V V W T N I F M R 3 V L V L L L V T L V L L F L N I A L I N 4 F N A L S L T F P I L F F V T S T L L V 5 V I T S L L L Y A I F S V S F F L P L W 6 C S Q G S P Y S M T L V Q C F I F I L 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available