LPA6 receptor (q08bg4_danre)

FAMILY

Class A (Rhodopsin) Lipid receptors Lysophospholipid (LPA) receptors LPA6 receptor

GENE

zgc:153784 (, lpar6, lpar6a, )

ORGANISM

Zebrafish (Danio rerio)

ALT. NAMES

Lysophosphatidic acid receptor 6, Lysophosphatidic acid receptor 6a, Zgc:153784, Zgc:153784 protein

SOURCE

TREMBL

SEQUENCE

N-term        
M
Y
N
T
S
L
E
M
E
M
10
                   
L
N
V
S
N
V
T
H
C
P
20
          TM1    
K
N
D
N
F
K
Y
P
L
Y
30
                   
S
M
V
F
S
I
V
F
M
V
40
                   
G
L
I
T
N
V
A
A
M
Y
50
          ICL1  
I
F
M
C
S
L
K
L
R
N
60
TM2              
E
T
T
T
Y
M
M
N
L
V
70
                   
V
S
D
L
L
F
V
L
T
L
80
                   
P
L
R
V
F
Y
F
V
Q
Q
90
ECL1 TM3      
N
W
P
F
G
S
L
L
C
K
100
                   
L
S
V
S
L
F
Y
T
N
M
110
                   
Y
G
S
I
L
F
L
T
C
I
120
                   
S
V
D
R
F
L
A
I
V
Y
130
ICL2            
P
F
R
S
R
G
L
R
T
K
140
TM4              
R
N
A
K
I
V
C
A
A
V
150
                   
W
V
L
V
L
S
G
S
L
P
160
            ECL2
T
G
F
M
L
N
S
T
N
K
170
                   
L
E
N
N
S
I
S
C
F
E
180
            TM5  
N
F
S
S
K
E
W
K
S
H
190
                   
L
S
K
V
V
I
F
I
E
T
200
                   
V
G
F
L
I
P
L
M
L
N
210
                   
V
V
C
S
A
M
V
L
Q
T
220
        ICL3    
L
R
R
P
N
T
V
S
R
G
230
TM6              
G
K
L
N
K
K
K
I
L
R
240
                   
M
I
I
V
H
L
F
I
F
C
250
                   
F
C
F
I
P
Y
N
V
N
L
260
                   
V
F
Y
S
L
V
R
T
N
T
270
ECL3 TM7      
L
K
G
C
A
A
E
S
V
V
280
                   
R
T
I
Y
P
I
A
L
C
I
290
                   
A
V
S
N
C
C
F
D
P
I
300
          H8      
V
Y
Y
F
T
S
E
T
I
Q
310
                   
N
S
I
K
R
K
T
Q
T
G
320
C-term        
H
S
I
D
V
K
F
S
E
A
330
                   
L
Q
S
E
T
S
S
T
L
Q
340
                   
F
S
L
R
S
I
K
N
K
M
350
             
F
H
N
E
S
H
V

LINKS

DIAGRAMS

7TM

ICL1 L K L R ICL1ECL1 Q N W P F ECL1ICL2 P F R S R G L R ICL2ECL2 S T N K L E N N S I S C F E N F S S K E ECL2ICL3 N T V S ICL3ECL3 T L K ECL3N-term M Y N T S L E M E M L N V S N V T H C P K N D N F N-termC-term H S I D V K F S E A L Q S E T S S T L Q F S L R S I K N K M F H N E S H V C-term K Y P L Y S M V F S I V F M V G L I T N V A A M Y I F M C S N E T T T Y M M N L V V S D L L F V L T L P L R V F Y F V Q G S L L C K L S V S L F Y T N M Y G S I L F L T C I S V D R F L A I V Y T K R N A K I V C A A V W V L V L S G S L P T G F M L N W K S H L S K V V I F I E T V G F L I P L M L N V V C S A M V L Q T L R R P R G G K L N K K K I L R M I I V H L F I F C F C F I P Y N V N L V F Y S L V R T N G C A A E S V V R T I Y P I A L C I A V S N C C F D P I V Y Y F T S E T I K R G I Q N S K T Q T
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

V N T I L G V M F V I S F V M S Y L P Y 1 M N L V V S D L L F V L T L P L R V F Y 2 C T L F L I S G Y M N T Y F L S V S L K 3 A K I V C A A V W V L V L S G S L P T G 4 S C V V N L M L P I L F G V T E I F I V V 5 I V H L F I F C F C F I P Y N V N L V F 6 I P D F C C N S V A I C L A I P Y I T 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

No structure models have been generated as experimental structures are available (see below).

STRUCTURES

Found 1 structure(s) - view all details on the Structures page

PDBs: 5XSZ