TAS2R20 (t2r20_human)

FAMILY

Class T (Taste 2) Sensory receptors Taste 2 receptors TAS2R20

GENE

TAS2R20 (TAS2R49)

ORGANISM

Human (Homo sapiens)

ALT. NAMES

Taste receptor type 2 member 20, Taste receptor type 2 member 49, T2R49, Taste receptor type 2 member 56, T2R56

SOURCE

SWISSPROT

SEQUENCE

N-term TM1  
M
M
S
F
L
H
I
V
F
S
10
                   
I
L
V
V
V
A
F
I
L
G
20
                   
N
F
A
N
G
F
I
A
L
I
30
                   
N
F
I
A
W
V
K
R
Q
K
40
ICL1 TM2      
I
S
S
A
D
Q
I
I
A
A
50
                   
L
A
V
S
R
V
G
L
L
W
60
                   
V
I
L
L
H
W
Y
S
T
V
70
    ECL1 TM3  
L
N
P
T
S
S
N
L
K
V
80
                   
I
I
F
I
S
N
A
W
A
V
90
                   
T
N
H
F
S
I
W
L
A
T
100
                   
S
L
S
I
F
Y
L
L
K
I
110
  ICL2          
V
N
F
S
R
L
I
F
H
H
120
      TM4        
L
K
R
K
A
K
S
V
V
L
130
                   
V
I
V
L
G
S
L
F
F
L
140
                   
V
C
H
L
V
M
K
H
T
Y
150
    ECL2        
I
N
V
W
T
E
E
C
E
G
160
                   
N
V
T
W
K
I
K
L
R
N
170
          TM5    
A
M
H
L
S
N
L
T
V
A
180
                   
M
L
A
N
L
I
P
F
T
L
190
                   
T
L
I
S
F
L
L
L
I
Y
200
                   
S
L
C
K
H
L
K
K
M
Q
210
      ICL3 TM6
L
H
G
K
G
S
Q
D
P
S
220
                   
T
K
I
H
I
K
A
L
Q
T
230
                   
V
T
S
F
L
I
L
L
A
I
240
                   
Y
F
L
C
L
I
I
S
F
W
250
        ECL3 TM7
N
F
K
M
R
P
K
E
I
V
260
                 
L
M
L
C
Q
A
F
G
I
I
270
                   
Y
P
S
F
H
S
F
I
L
I
280
    H8            
W
G
N
K
T
L
K
Q
T
F
290
                   
L
S
V
L
W
Q
V
T
C
W
300
  C-term    
A
K
G
Q
N
Q
S
T
P

LINKS

BitterDB

Guide To Pharmacology

UniProt

DIAGRAMS

ICL1 K I ICL1ECL1 P T S S ECL1ICL2 N F S R L I F H H L K R ICL2ECL2 V W T E E C E G N V T W K I K L R N A M H L S ECL2ICL3 K G S Q ICL3ECL3 R P K ECL3N-term M N-termC-term K G Q N Q S T P C-term M S F L H I V F S I L V V V A F I L G N F A N G F I A L I N F I A W V K R Q S S A D Q I I A A L A V S R V G L L W V I L L H W Y S T V L N N L K V I I F I S N A W A V T N H F S I W L A T S L S I F Y L L K I V K A K S V V L V I V L G S L F F L V C H L V M K H T Y I N N L T V A M L A N L I P F T L T L I S F L L L I Y S L C K H L K K M Q L H G D P S T K I H I K A L Q T V T S F L I L L A I Y F L C L I I S F W N F K M E I V L M L C Q A F G I I Y P S F H S F I L I W G N K T F L S V T C L K Q T V L W Q W A
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

G N A F N G L I F A V V V L I S F V I H 1 A A L A V S R V G L L W V I L L H W Y S 2 S T A L W I S F H N T V A W A N S I F I 3 V L V I V L G S L F F L V C H L V M K H 4 F S I L T L T F P I L N A L M A V T L N 5 V T S F L I L L A I Y F L C L I I S F W 6 F S H F S P Y I I G F A Q C L M L V I 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

ENDOGENOUS LIGANDS

No endogenous ligands available

STRUCTURE MODELS

t2r20_human inactive,

t2r20_human active

STRUCTURES

No structures available