TAS2R5 (tr105_mouse)

FAMILY

Class T (Taste 2) Sensory receptors Taste 2 receptors TAS2R5

GENE

Tas2r105 (Tas2r5, Tas2r9)

ORGANISM

Mouse (Mus musculus)

ALT. NAMES

Taste receptor type 2 member 105, T2R105, Taste receptor type 2 member 5, T2R5, Taste receptor type 2 member 9, T2R9

SOURCE

SWISSPROT

SEQUENCE

N-term TM1  
M
L
S
A
A
E
G
I
L
L
10
                   
S
I
A
T
V
E
A
G
L
G
20
                   
V
L
G
N
T
F
I
A
L
V
30
                   
N
C
M
D
W
A
K
N
N
K
40
ICL1 TM2      
L
S
M
T
G
F
L
L
I
G
50
                   
L
A
T
S
R
I
F
I
V
W
60
                   
L
L
T
L
D
A
Y
A
K
L
70
    ECL1        
F
Y
P
S
K
Y
F
S
S
S
80
TM3              
L
I
E
I
I
S
Y
I
W
M
90
                   
T
V
N
H
L
T
V
W
F
A
100
                   
T
S
L
S
I
F
Y
F
L
K
110
    ICL2        
I
A
N
F
S
D
C
V
F
L
120
              TM4
W
L
K
R
R
T
D
K
A
F
130
                   
V
F
L
L
G
C
L
L
T
S
140
                   
W
V
I
S
F
S
F
V
V
K
150
            ECL2
V
M
K
D
G
K
V
N
H
R
160
                   
N
R
T
S
E
M
Y
W
E
K
170
          TM5    
R
Q
F
T
I
N
Y
V
F
L
180
                   
N
I
G
V
I
S
L
F
M
M
190
                   
T
L
T
A
C
F
L
L
I
M
200
                   
S
L
W
R
H
S
R
Q
M
Q
210
      ICL3 TM6
S
G
V
S
G
F
R
D
L
N
220
                   
T
E
A
H
V
K
A
I
K
F
230
                   
L
I
S
F
I
I
L
F
V
L
240
                   
Y
F
I
G
V
S
I
E
I
I
250
        ECL3 TM7
C
I
F
I
P
E
N
K
L
L
260
                 
F
I
F
G
F
T
T
A
S
I
270
                   
Y
P
C
C
H
S
F
I
L
I
280
    H8            
L
S
N
S
Q
L
K
Q
A
F
290
                   
V
K
V
L
Q
G
L
K
F
F
300

LINKS

UniProt

DIAGRAMS

ICL1 K L ICL1ECL1 P S K Y F S S S ECL1ICL2 N F S D C V F L W L K R R T D ICL2ECL2 V N H R N R T S E M Y W E K R Q F T I ECL2ICL3 S G F R ICL3ECL3 P E N ECL3N-term M N-term L S A A E G I L L S I A T V E A G L G V L G N T F I A L V N C M D W A K N N S M T G F L L I G L A T S R I F I V W L L T L D A Y A K L F Y L I E I I S Y I W M T V N H L T V W F A T S L S I F Y F L K I A K A F V F L L G C L L T S W V I S F S F V V K V M K D G K N Y V F L N I G V I S L F M M T L T A C F L L I M S L W R H S R Q M Q S G V D L N T E A H V K A I K F L I S F I I L F V L Y F I G V S I E I I C I F I K L L F I F G F T T A S I Y P C C H S F I L I L S N S Q F V K L K F L K Q A V L Q G F
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

T N G L V G L G A E V T A I S L L I G E 1 I G L A T S R I F I V W L L T L D A Y A 2 S T A F W V T L H N V T M W I Y S I I E 3 L L G C L L T S W V I S F S F V V K V M 4 C A T L T M M F L S I V G I N L F V Y N 5 L I S F I I L F V L Y F I G V S I E I I 6 F S H C C P Y I S A T T F G F I F L L 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

ENDOGENOUS LIGANDS

No endogenous ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available