Refined structure (7X9B) of Gi1 -
Y2 receptor
GPCR CLASS (FAMILY)
SPECIES
G PROTEIN FAMILY
DATE
3D VIEW
REFINED G PROTEIN RESIDUES
Residue sidechains - 193 from structure (54.5%), 161 from model (45.5%)
Segment | Seq.num. | AA | CGN# | Backbone from | Sidechain from |
---|---|---|---|---|---|
G.HN | 1 | M | G.HN.01 | AF2 | AF2 |
G.HN | 2 | G | G.HN.02 | AF2 | AF2 |
G.HN | 3 | C | G.HN.09 | AF2 | AF2 |
G.HN | 4 | T | G.HN.10 | AF2 | AF2 |
G.HN | 5 | L | G.HN.11 | Structure | Structure |
G.HN | 6 | S | G.HN.30 | Structure | Structure |
G.HN | 7 | A | G.HN.31 | Structure | Structure |
G.HN | 8 | E | G.HN.32 | Structure | AF2 |
G.HN | 9 | D | G.HN.33 | Structure | AF2 |
G.HN | 10 | K | G.HN.34 | Structure | Structure |
G.HN | 11 | A | G.HN.35 | Structure | Structure |
G.HN | 12 | A | G.HN.36 | Structure | Structure |
G.HN | 13 | V | G.HN.37 | Structure | Structure |
G.HN | 14 | E | G.HN.38 | Structure | Structure |
G.HN | 15 | R | G.HN.39 | Structure | Structure |
G.HN | 16 | S | G.HN.40 | Structure | Structure |
G.HN | 17 | K | G.HN.41 | Structure | Structure |
G.HN | 18 | M | G.HN.42 | Structure | Structure |
G.HN | 19 | I | G.HN.43 | Structure | Structure |
G.HN | 20 | D | G.HN.44 | Structure | Structure |
G.HN | 21 | R | G.HN.45 | Structure | Structure |
G.HN | 22 | N | G.HN.46 | Structure | Structure |
G.HN | 23 | L | G.HN.47 | Structure | Structure |
G.HN | 24 | R | G.HN.48 | Structure | Structure |
G.HN | 25 | E | G.HN.49 | Structure | Structure |
G.HN | 26 | D | G.HN.50 | Structure | Structure |
G.HN | 27 | G | G.HN.51 | Structure | Structure |
G.HN | 28 | E | G.HN.52 | Structure | Structure |
G.HN | 29 | K | G.HN.53 | Structure | Structure |
G.hns1 | 30 | A | G.hns1.01 | Structure | Structure |
G.hns1 | 31 | A | G.hns1.02 | Structure | Structure |
G.hns1 | 32 | R | G.hns1.03 | Structure | Structure |
G.S1 | 33 | E | G.S1.01 | Structure | Structure |
G.S1 | 34 | V | G.S1.02 | Structure | Structure |
G.S1 | 35 | K | G.S1.03 | Structure | Structure |
G.S1 | 36 | L | G.S1.04 | Structure | Structure |
G.S1 | 37 | L | G.S1.05 | Structure | Structure |
G.S1 | 38 | L | G.S1.06 | Structure | Structure |
G.S1 | 39 | L | G.S1.07 | Structure | Structure |
G.s1h1 | 40 | G | G.s1h1.01 | Structure | Structure |
G.s1h1 | 41 | A | G.s1h1.02 | Structure | Structure |
G.s1h1 | 42 | G | G.s1h1.03 | Structure | Structure |
G.s1h1 | 43 | E | G.s1h1.04 | Structure | AF2 |
G.s1h1 | 44 | S | G.s1h1.05 | Structure | Structure |
G.s1h1 | 45 | G | G.s1h1.06 | Structure | Structure |
G.H1 | 46 | K | G.H1.01 | Structure | Structure |
G.H1 | 47 | S | G.H1.02 | Structure | AF2 |
G.H1 | 48 | T | G.H1.03 | Structure | Structure |
G.H1 | 49 | I | G.H1.04 | Structure | Structure |
G.H1 | 50 | V | G.H1.05 | Structure | Structure |
G.H1 | 51 | K | G.H1.06 | Structure | AF2 |
G.H1 | 52 | Q | G.H1.07 | Structure | Structure |
G.H1 | 53 | M | G.H1.08 | Structure | Structure |
G.H1 | 54 | K | G.H1.09 | Structure | Structure |
G.H1 | 55 | I | G.H1.10 | Structure | AF2 |
G.H1 | 56 | I | G.H1.11 | AF2 | AF2 |
G.H1 | 57 | H | G.H1.12 | AF2 | AF2 |
G.h1ha | 58 | E | G.h1ha.01 | AF2 | AF2 |
G.h1ha | 59 | A | G.h1ha.02 | AF2 | AF2 |
G.h1ha | 60 | G | G.h1ha.03 | AF2 | AF2 |
G.h1ha | 61 | Y | G.h1ha.04 | AF2 | AF2 |
G.h1ha | 62 | S | G.h1ha.05 | AF2 | AF2 |
H.HA | 63 | E | H.HA.01 | AF2 | AF2 |
H.HA | 64 | E | H.HA.02 | AF2 | AF2 |
H.HA | 65 | E | H.HA.03 | AF2 | AF2 |
H.HA | 66 | C | H.HA.04 | AF2 | AF2 |
H.HA | 67 | K | H.HA.05 | AF2 | AF2 |
H.HA | 68 | Q | H.HA.06 | AF2 | AF2 |
H.HA | 69 | Y | H.HA.07 | AF2 | AF2 |
H.HA | 70 | K | H.HA.08 | AF2 | AF2 |
H.HA | 71 | A | H.HA.09 | AF2 | AF2 |
H.HA | 72 | V | H.HA.10 | AF2 | AF2 |
H.HA | 73 | V | H.HA.11 | AF2 | AF2 |
H.HA | 74 | Y | H.HA.12 | AF2 | AF2 |
H.HA | 75 | S | H.HA.13 | AF2 | AF2 |
H.HA | 76 | N | H.HA.14 | AF2 | AF2 |
H.HA | 77 | T | H.HA.15 | AF2 | AF2 |
H.HA | 78 | I | H.HA.16 | AF2 | AF2 |
H.HA | 79 | Q | H.HA.17 | AF2 | AF2 |
H.HA | 80 | S | H.HA.18 | AF2 | AF2 |
H.HA | 81 | I | H.HA.19 | AF2 | AF2 |
H.HA | 82 | I | H.HA.20 | AF2 | AF2 |
H.HA | 83 | A | H.HA.21 | AF2 | AF2 |
H.HA | 84 | I | H.HA.22 | AF2 | AF2 |
H.HA | 85 | I | H.HA.23 | AF2 | AF2 |
H.HA | 86 | R | H.HA.24 | AF2 | AF2 |
H.HA | 87 | A | H.HA.25 | AF2 | AF2 |
H.HA | 88 | M | H.HA.26 | AF2 | AF2 |
H.HA | 89 | G | H.HA.27 | AF2 | AF2 |
H.HA | 90 | R | H.HA.28 | AF2 | AF2 |
H.HA | 91 | L | H.HA.29 | AF2 | AF2 |
H.hahb | 92 | K | H.hahb.01 | AF2 | AF2 |
H.hahb | 93 | I | H.hahb.04 | AF2 | AF2 |
H.hahb | 94 | D | H.hahb.05 | AF2 | AF2 |
H.hahb | 95 | F | H.hahb.06 | AF2 | AF2 |
H.hahb | 96 | G | H.hahb.07 | AF2 | AF2 |
H.hahb | 97 | D | H.hahb.08 | AF2 | AF2 |
H.hahb | 98 | S | H.hahb.09 | AF2 | AF2 |
H.HB | 99 | A | H.HB.01 | AF2 | AF2 |
H.HB | 100 | R | H.HB.02 | AF2 | AF2 |
H.HB | 101 | A | H.HB.03 | AF2 | AF2 |
H.HB | 102 | D | H.HB.04 | AF2 | AF2 |
H.HB | 103 | D | H.HB.05 | AF2 | AF2 |
H.HB | 104 | A | H.HB.06 | AF2 | AF2 |
H.HB | 105 | R | H.HB.07 | AF2 | AF2 |
H.HB | 106 | Q | H.HB.08 | AF2 | AF2 |
H.HB | 107 | L | H.HB.09 | AF2 | AF2 |
H.HB | 108 | F | H.HB.10 | AF2 | AF2 |
H.HB | 109 | V | H.HB.11 | AF2 | AF2 |
H.HB | 110 | L | H.HB.12 | AF2 | AF2 |
H.HB | 111 | A | H.HB.13 | AF2 | AF2 |
H.HB | 112 | G | H.HB.14 | AF2 | AF2 |
H.hbhc | 113 | A | H.hbhc.01 | AF2 | AF2 |
H.hbhc | 114 | A | H.hbhc.02 | AF2 | AF2 |
H.hbhc | 115 | E | H.hbhc.03 | AF2 | AF2 |
H.hbhc | 116 | E | H.hbhc.04 | AF2 | AF2 |
H.hbhc | 117 | G | H.hbhc.12 | AF2 | AF2 |
H.hbhc | 118 | F | H.hbhc.13 | AF2 | AF2 |
H.hbhc | 119 | M | H.hbhc.14 | AF2 | AF2 |
H.hbhc | 120 | T | H.hbhc.15 | AF2 | AF2 |
H.HC | 121 | A | H.HC.01 | AF2 | AF2 |
H.HC | 122 | E | H.HC.02 | AF2 | AF2 |
H.HC | 123 | L | H.HC.03 | AF2 | AF2 |
H.HC | 124 | A | H.HC.04 | AF2 | AF2 |
H.HC | 125 | G | H.HC.05 | AF2 | AF2 |
H.HC | 126 | V | H.HC.06 | AF2 | AF2 |
H.HC | 127 | I | H.HC.07 | AF2 | AF2 |
H.HC | 128 | K | H.HC.08 | AF2 | AF2 |
H.HC | 129 | R | H.HC.09 | AF2 | AF2 |
H.HC | 130 | L | H.HC.10 | AF2 | AF2 |
H.HC | 131 | W | H.HC.11 | AF2 | AF2 |
H.HC | 132 | K | H.HC.12 | AF2 | AF2 |
H.hchd | 133 | D | H.hchd.01 | AF2 | AF2 |
H.HD | 134 | S | H.HD.01 | AF2 | AF2 |
H.HD | 135 | G | H.HD.02 | AF2 | AF2 |
H.HD | 136 | V | H.HD.03 | AF2 | AF2 |
H.HD | 137 | Q | H.HD.04 | AF2 | AF2 |
H.HD | 138 | A | H.HD.05 | AF2 | AF2 |
H.HD | 139 | C | H.HD.06 | AF2 | AF2 |
H.HD | 140 | F | H.HD.07 | AF2 | AF2 |
H.HD | 141 | N | H.HD.08 | AF2 | AF2 |
H.HD | 142 | R | H.HD.09 | AF2 | AF2 |
H.HD | 143 | S | H.HD.10 | AF2 | AF2 |
H.HD | 144 | R | H.HD.11 | AF2 | AF2 |
H.HD | 145 | E | H.HD.12 | AF2 | AF2 |
H.hdhe | 146 | Y | H.hdhe.01 | AF2 | AF2 |
H.hdhe | 147 | Q | H.hdhe.02 | AF2 | AF2 |
H.hdhe | 148 | L | H.hdhe.03 | AF2 | AF2 |
H.hdhe | 149 | N | H.hdhe.04 | AF2 | AF2 |
H.hdhe | 150 | D | H.hdhe.05 | AF2 | AF2 |
H.HE | 151 | S | H.HE.01 | AF2 | AF2 |
H.HE | 152 | A | H.HE.02 | AF2 | AF2 |
H.HE | 153 | A | H.HE.03 | AF2 | AF2 |
H.HE | 154 | Y | H.HE.04 | AF2 | AF2 |
H.HE | 155 | Y | H.HE.05 | AF2 | AF2 |
H.HE | 156 | L | H.HE.06 | AF2 | AF2 |
H.HE | 157 | N | H.HE.07 | AF2 | AF2 |
H.HE | 158 | D | H.HE.08 | AF2 | AF2 |
H.HE | 159 | L | H.HE.09 | AF2 | AF2 |
H.HE | 160 | D | H.HE.10 | AF2 | AF2 |
H.HE | 161 | R | H.HE.11 | AF2 | AF2 |
H.HE | 162 | I | H.HE.12 | AF2 | AF2 |
H.HE | 163 | A | H.HE.13 | AF2 | AF2 |
H.hehf | 164 | Q | H.hehf.01 | AF2 | AF2 |
H.hehf | 165 | P | H.hehf.02 | AF2 | AF2 |
H.hehf | 166 | N | H.hehf.03 | AF2 | AF2 |
H.hehf | 167 | Y | H.hehf.04 | AF2 | AF2 |
H.hehf | 168 | I | H.hehf.05 | AF2 | AF2 |
H.hehf | 169 | P | H.hehf.06 | AF2 | AF2 |
H.hehf | 170 | T | H.hehf.07 | AF2 | AF2 |
H.HF | 171 | Q | H.HF.01 | AF2 | AF2 |
H.HF | 172 | Q | H.HF.02 | AF2 | AF2 |
H.HF | 173 | D | H.HF.03 | AF2 | AF2 |
H.HF | 174 | V | H.HF.04 | AF2 | AF2 |
H.HF | 175 | L | H.HF.05 | AF2 | AF2 |
H.HF | 176 | R | H.HF.06 | AF2 | AF2 |
G.hfs2 | 177 | T | G.hfs2.01 | AF2 | AF2 |
G.hfs2 | 178 | R | G.hfs2.02 | AF2 | AF2 |
G.hfs2 | 179 | V | G.hfs2.03 | AF2 | AF2 |
G.hfs2 | 180 | K | G.hfs2.04 | AF2 | AF2 |
G.hfs2 | 181 | T | G.hfs2.05 | AF2 | AF2 |
G.hfs2 | 182 | T | G.hfs2.06 | Structure | Structure |
G.hfs2 | 183 | G | G.hfs2.07 | Structure | Structure |
G.S2 | 184 | I | G.S2.01 | Structure | Structure |
G.S2 | 185 | V | G.S2.02 | Structure | Structure |
G.S2 | 186 | E | G.S2.03 | Structure | Structure |
G.S2 | 187 | T | G.S2.04 | Structure | Structure |
G.S2 | 188 | H | G.S2.05 | Structure | Structure |
G.S2 | 189 | F | G.S2.06 | Structure | Structure |
G.S2 | 190 | T | G.S2.07 | Structure | Structure |
G.S2 | 191 | F | G.S2.08 | Structure | Structure |
G.s2s3 | 192 | K | G.s2s3.01 | Structure | Structure |
G.s2s3 | 193 | D | G.s2s3.02 | Structure | AF2 |
G.S3 | 194 | L | G.S3.01 | Structure | Structure |
G.S3 | 195 | H | G.S3.02 | Structure | Structure |
G.S3 | 196 | F | G.S3.03 | Structure | Structure |
G.S3 | 197 | K | G.S3.04 | Structure | Structure |
G.S3 | 198 | M | G.S3.05 | Structure | Structure |
G.S3 | 199 | F | G.S3.06 | Structure | Structure |
G.S3 | 200 | D | G.S3.07 | Structure | Structure |
G.S3 | 201 | V | G.S3.08 | Structure | Structure |
G.s3h2 | 202 | G | G.s3h2.01 | Structure | Structure |
G.s3h2 | 203 | G | G.s3h2.02 | Structure | AF2 |
G.s3h2 | 204 | Q | G.s3h2.03 | Structure | Structure |
G.H2 | 205 | R | G.H2.01 | Structure | Structure |
G.H2 | 206 | S | G.H2.02 | Structure | Structure |
G.H2 | 207 | E | G.H2.03 | Structure | AF2 |
G.H2 | 208 | R | G.H2.04 | Structure | Structure |
G.H2 | 209 | K | G.H2.05 | Structure | Structure |
G.H2 | 210 | K | G.H2.06 | Structure | Structure |
G.H2 | 211 | W | G.H2.07 | Structure | Structure |
G.H2 | 212 | I | G.H2.08 | Structure | Structure |
G.H2 | 213 | H | G.H2.09 | Structure | Structure |
G.H2 | 214 | C | G.H2.10 | Structure | Structure |
G.h2s4 | 215 | F | G.h2s4.01 | Structure | Structure |
G.h2s4 | 216 | E | G.h2s4.02 | Structure | Structure |
G.h2s4 | 217 | G | G.h2s4.03 | Structure | Structure |
G.h2s4 | 218 | V | G.h2s4.04 | Structure | Structure |
G.h2s4 | 219 | T | G.h2s4.05 | Structure | Structure |
G.S4 | 220 | A | G.S4.01 | Structure | Structure |
G.S4 | 221 | I | G.S4.02 | Structure | Structure |
G.S4 | 222 | I | G.S4.03 | Structure | Structure |
G.S4 | 223 | F | G.S4.04 | Structure | Structure |
G.S4 | 224 | C | G.S4.05 | Structure | Structure |
G.S4 | 225 | V | G.S4.06 | Structure | Structure |
G.S4 | 226 | A | G.S4.07 | Structure | Structure |
G.s4h3 | 227 | L | G.s4h3.01 | Structure | Structure |
G.s4h3 | 228 | S | G.s4h3.02 | Structure | Structure |
G.s4h3 | 229 | D | G.s4h3.03 | Structure | AF2 |
G.s4h3 | 230 | Y | G.s4h3.04 | Structure | Structure |
G.s4h3 | 231 | D | G.s4h3.05 | Structure | Structure |
G.s4h3 | 232 | L | G.s4h3.06 | Structure | AF2 |
G.s4h3 | 233 | V | G.s4h3.07 | Structure | Structure |
G.s4h3 | 234 | L | G.s4h3.08 | AF2 | AF2 |
G.s4h3 | 235 | A | G.s4h3.09 | AF2 | AF2 |
G.s4h3 | 236 | E | G.s4h3.10 | AF2 | AF2 |
G.s4h3 | 237 | D | G.s4h3.11 | AF2 | AF2 |
G.s4h3 | 238 | E | G.s4h3.12 | AF2 | AF2 |
G.s4h3 | 239 | E | G.s4h3.13 | AF2 | AF2 |
G.s4h3 | 240 | M | G.s4h3.14 | Structure | Structure |
G.s4h3 | 241 | N | G.s4h3.15 | Structure | Structure |
G.H3 | 242 | R | G.H3.01 | Structure | Structure |
G.H3 | 243 | M | G.H3.02 | Structure | Structure |
G.H3 | 244 | H | G.H3.03 | Structure | Structure |
G.H3 | 245 | E | G.H3.04 | Structure | AF2 |
G.H3 | 246 | S | G.H3.05 | Structure | Structure |
G.H3 | 247 | M | G.H3.06 | Structure | AF2 |
G.H3 | 248 | K | G.H3.07 | Structure | Structure |
G.H3 | 249 | L | G.H3.08 | Structure | Structure |
G.H3 | 250 | F | G.H3.09 | Structure | Structure |
G.H3 | 251 | D | G.H3.10 | Structure | Structure |
G.H3 | 252 | S | G.H3.11 | Structure | Structure |
G.H3 | 253 | I | G.H3.12 | Structure | Structure |
G.H3 | 254 | C | G.H3.13 | Structure | Structure |
G.H3 | 255 | N | G.H3.14 | Structure | Structure |
G.H3 | 256 | N | G.H3.15 | Structure | Structure |
G.H3 | 257 | K | G.H3.16 | Structure | Structure |
G.H3 | 258 | W | G.H3.17 | Structure | Structure |
G.H3 | 259 | F | G.H3.18 | Structure | Structure |
G.h3s5 | 260 | T | G.h3s5.01 | Structure | Structure |
G.h3s5 | 261 | D | G.h3s5.02 | Structure | Structure |
G.h3s5 | 262 | T | G.h3s5.03 | Structure | Structure |
G.S5 | 263 | S | G.S5.01 | Structure | Structure |
G.S5 | 264 | I | G.S5.02 | Structure | Structure |
G.S5 | 265 | I | G.S5.03 | Structure | Structure |
G.S5 | 266 | L | G.S5.04 | Structure | Structure |
G.S5 | 267 | F | G.S5.05 | Structure | Structure |
G.S5 | 268 | L | G.S5.06 | Structure | Structure |
G.S5 | 269 | N | G.S5.07 | Structure | Structure |
G.s5hg | 270 | K | G.s5hg.01 | Structure | Structure |
G.HG | 271 | K | G.HG.01 | Structure | AF2 |
G.HG | 272 | D | G.HG.02 | Structure | AF2 |
G.HG | 273 | L | G.HG.03 | Structure | Structure |
G.HG | 274 | F | G.HG.04 | Structure | Structure |
G.HG | 275 | E | G.HG.05 | Structure | Structure |
G.HG | 276 | E | G.HG.06 | Structure | Structure |
G.HG | 277 | K | G.HG.07 | Structure | AF2 |
G.HG | 278 | I | G.HG.08 | Structure | Structure |
G.HG | 279 | K | G.HG.09 | Structure | AF2 |
G.HG | 280 | K | G.HG.12 | Structure | AF2 |
G.HG | 281 | S | G.HG.13 | Structure | Structure |
G.HG | 282 | P | G.HG.14 | Structure | Structure |
G.HG | 283 | L | G.HG.15 | Structure | Structure |
G.HG | 284 | T | G.HG.16 | Structure | Structure |
G.HG | 285 | I | G.HG.17 | Structure | Structure |
G.hgh4 | 286 | C | G.hgh4.01 | Structure | Structure |
G.hgh4 | 287 | Y | G.hgh4.02 | Structure | Structure |
G.hgh4 | 288 | P | G.hgh4.03 | Structure | Structure |
G.hgh4 | 289 | E | G.hgh4.04 | Structure | AF2 |
G.hgh4 | 290 | Y | G.hgh4.05 | Structure | Structure |
G.hgh4 | 291 | A | G.hgh4.06 | Structure | Structure |
G.hgh4 | 292 | G | G.hgh4.07 | Structure | Structure |
G.hgh4 | 293 | S | G.hgh4.08 | Structure | Structure |
G.H4 | 294 | N | G.H4.01 | Structure | Structure |
G.H4 | 295 | T | G.H4.02 | Structure | Structure |
G.H4 | 296 | Y | G.H4.03 | Structure | Structure |
G.H4 | 297 | E | G.H4.04 | Structure | AF2 |
G.H4 | 298 | E | G.H4.05 | Structure | Structure |
G.H4 | 299 | A | G.H4.06 | Structure | Structure |
G.H4 | 300 | A | G.H4.07 | Structure | Structure |
G.H4 | 301 | A | G.H4.08 | Structure | Structure |
G.H4 | 302 | Y | G.H4.10 | Structure | Structure |
G.H4 | 303 | I | G.H4.11 | Structure | Structure |
G.H4 | 304 | Q | G.H4.12 | Structure | Structure |
G.H4 | 305 | C | G.H4.13 | Structure | Structure |
G.H4 | 306 | Q | G.H4.14 | Structure | Structure |
G.H4 | 307 | F | G.H4.15 | Structure | Structure |
G.H4 | 308 | E | G.H4.16 | Structure | Structure |
G.H4 | 309 | D | G.H4.17 | Structure | Structure |
G.h4s6 | 310 | L | G.h4s6.01 | Structure | Structure |
G.h4s6 | 311 | N | G.h4s6.02 | Structure | Structure |
G.h4s6 | 312 | K | G.h4s6.03 | Structure | Structure |
G.h4s6 | 313 | R | G.h4s6.04 | Structure | Structure |
G.h4s6 | 314 | K | G.h4s6.08 | Structure | Structure |
G.h4s6 | 315 | D | G.h4s6.09 | Structure | Structure |
G.h4s6 | 316 | T | G.h4s6.10 | Structure | Structure |
G.h4s6 | 317 | K | G.h4s6.11 | Structure | Structure |
G.h4s6 | 318 | E | G.h4s6.12 | Structure | AF2 |
G.S6 | 319 | I | G.S6.01 | Structure | Structure |
G.S6 | 320 | Y | G.S6.02 | Structure | Structure |
G.S6 | 321 | T | G.S6.03 | Structure | Structure |
G.S6 | 322 | H | G.S6.04 | Structure | Structure |
G.S6 | 323 | F | G.S6.05 | Structure | Structure |
G.s6h5 | 324 | T | G.s6h5.01 | Structure | Structure |
G.s6h5 | 325 | C | G.s6h5.02 | Structure | Structure |
G.s6h5 | 326 | A | G.s6h5.03 | Structure | AF2 |
G.s6h5 | 327 | T | G.s6h5.04 | Structure | AF2 |
G.s6h5 | 328 | D | G.s6h5.05 | Structure | AF2 |
G.H5 | 329 | T | G.H5.01 | Structure | Structure |
G.H5 | 330 | K | G.H5.02 | Structure | AF2 |
G.H5 | 331 | N | G.H5.03 | Structure | Structure |
G.H5 | 332 | V | G.H5.04 | Structure | Structure |
G.H5 | 333 | Q | G.H5.05 | Structure | Structure |
G.H5 | 334 | F | G.H5.06 | Structure | Structure |
G.H5 | 335 | V | G.H5.07 | Structure | Structure |
G.H5 | 336 | F | G.H5.08 | Structure | Structure |
G.H5 | 337 | D | G.H5.09 | Structure | Structure |
G.H5 | 338 | A | G.H5.10 | Structure | Structure |
G.H5 | 339 | V | G.H5.11 | Structure | Structure |
G.H5 | 340 | T | G.H5.12 | Structure | Structure |
G.H5 | 341 | D | G.H5.13 | Structure | Structure |
G.H5 | 342 | V | G.H5.14 | Structure | Structure |
G.H5 | 343 | I | G.H5.15 | Structure | Structure |
G.H5 | 344 | I | G.H5.16 | Structure | Structure |
G.H5 | 345 | K | G.H5.17 | Structure | Structure |
G.H5 | 346 | N | G.H5.18 | Structure | Structure |
G.H5 | 347 | N | G.H5.19 | Structure | Structure |
G.H5 | 348 | L | G.H5.20 | Structure | Structure |
G.H5 | 349 | K | G.H5.21 | Structure | Structure |
G.H5 | 350 | D | G.H5.22 | Structure | Structure |
G.H5 | 351 | C | G.H5.23 | Structure | Structure |
G.H5 | 352 | G | G.H5.24 | Structure | Structure |
G.H5 | 353 | L | G.H5.25 | Structure | Structure |
G.H5 | 354 | F | G.H5.26 | Structure | Structure |
REFINED GPCR RESIDUES
Residue sidechains - 292 from structure (82.3%), 63 from model (17.7%)
Segment | Seq.num. | AA | GPCRdb# | Backbone from | Sidechain from |
---|---|---|---|---|---|
N-term | 1 | M | - | AF2 | AF2 |
N-term | 2 | G | - | AF2 | AF2 |
N-term | 3 | P | - | AF2 | AF2 |
N-term | 4 | I | - | AF2 | AF2 |
N-term | 5 | G | - | AF2 | AF2 |
N-term | 6 | A | - | AF2 | AF2 |
N-term | 7 | E | - | AF2 | AF2 |
N-term | 8 | A | - | AF2 | AF2 |
N-term | 9 | D | - | AF2 | AF2 |
N-term | 10 | E | - | AF2 | AF2 |
N-term | 11 | N | - | AF2 | AF2 |
N-term | 12 | Q | - | AF2 | AF2 |
N-term | 13 | T | - | AF2 | AF2 |
N-term | 14 | V | - | AF2 | AF2 |
N-term | 15 | E | - | AF2 | AF2 |
N-term | 16 | E | - | AF2 | AF2 |
N-term | 17 | M | - | AF2 | AF2 |
N-term | 18 | K | - | AF2 | AF2 |
N-term | 19 | V | - | AF2 | AF2 |
N-term | 20 | E | - | AF2 | AF2 |
N-term | 21 | Q | - | AF2 | AF2 |
N-term | 22 | Y | - | AF2 | AF2 |
N-term | 23 | G | - | AF2 | AF2 |
N-term | 24 | P | - | AF2 | AF2 |
N-term | 25 | Q | - | AF2 | AF2 |
N-term | 26 | T | - | AF2 | AF2 |
N-term | 27 | T | - | AF2 | AF2 |
N-term | 28 | P | - | AF2 | AF2 |
N-term | 29 | R | - | AF2 | AF2 |
N-term | 30 | G | - | AF2 | AF2 |
N-term | 31 | E | - | AF2 | AF2 |
N-term | 32 | L | - | AF2 | AF2 |
N-term | 33 | V | - | AF2 | AF2 |
N-term | 34 | P | - | AF2 | AF2 |
N-term | 35 | D | - | AF2 | AF2 |
N-term | 36 | P | - | AF2 | AF2 |
N-term | 37 | E | - | AF2 | AF2 |
N-term | 38 | P | - | AF2 | AF2 |
N-term | 39 | E | - | AF2 | AF2 |
N-term | 40 | L | - | Structure | Structure |
N-term | 41 | I | - | Structure | Structure |
N-term | 42 | D | - | Structure | Structure |
N-term | 43 | S | - | Structure | Structure |
N-term | 44 | T | - | Structure | Structure |
N-term | 45 | K | - | Structure | AF2 |
N-term | 46 | L | - | Structure | Structure |
N-term | 47 | I | - | Structure | Structure |
TM1 | 48 | E | 1.30x30 | Structure | AF2 |
TM1 | 49 | V | 1.31x31 | Structure | Structure |
TM1 | 50 | Q | 1.32x32 | Structure | AF2 |
TM1 | 51 | V | 1.33x33 | Structure | Structure |
TM1 | 52 | V | 1.34x34 | Structure | Structure |
TM1 | 53 | L | 1.35x35 | Structure | Structure |
TM1 | 54 | I | 1.36x36 | Structure | Structure |
TM1 | 55 | L | 1.37x37 | Structure | Structure |
TM1 | 56 | A | 1.38x38 | Structure | Structure |
TM1 | 57 | Y | 1.39x39 | Structure | Structure |
TM1 | 58 | C | 1.40x40 | Structure | Structure |
TM1 | 59 | S | 1.41x41 | Structure | Structure |
TM1 | 60 | I | 1.42x42 | Structure | Structure |
TM1 | 61 | I | 1.43x43 | Structure | Structure |
TM1 | 62 | L | 1.44x44 | Structure | Structure |
TM1 | 63 | L | 1.45x45 | Structure | Structure |
TM1 | 64 | G | 1.46x46 | Structure | Structure |
TM1 | 65 | V | 1.47x47 | Structure | Structure |
TM1 | 66 | I | 1.48x48 | Structure | Structure |
TM1 | 67 | G | 1.49x49 | Structure | Structure |
TM1 | 68 | N | 1.50x50 | Structure | Structure |
TM1 | 69 | S | 1.51x51 | Structure | Structure |
TM1 | 70 | L | 1.52x52 | Structure | Structure |
TM1 | 71 | V | 1.53x53 | Structure | Structure |
TM1 | 72 | I | 1.54x54 | Structure | Structure |
TM1 | 73 | H | 1.55x55 | Structure | Structure |
TM1 | 74 | V | 1.56x56 | Structure | Structure |
TM1 | 75 | V | 1.57x57 | Structure | Structure |
TM1 | 76 | I | 1.58x58 | Structure | Structure |
TM1 | 77 | K | 1.59x59 | Structure | Structure |
TM1 | 78 | F | 1.60x60 | Structure | Structure |
ICL1 | 79 | K | 12.48x48 | Structure | Structure |
ICL1 | 80 | S | 12.49x49 | Structure | Structure |
ICL1 | 81 | M | 12.50x50 | Structure | Structure |
ICL1 | 82 | R | 12.51x51 | Structure | Structure |
TM2 | 83 | T | 2.37x37 | Structure | Structure |
TM2 | 84 | V | 2.38x38 | Structure | Structure |
TM2 | 85 | T | 2.39x39 | Structure | Structure |
TM2 | 86 | N | 2.40x40 | Structure | Structure |
TM2 | 87 | F | 2.41x41 | Structure | Structure |
TM2 | 88 | F | 2.42x42 | Structure | Structure |
TM2 | 89 | I | 2.43x43 | Structure | Structure |
TM2 | 90 | A | 2.44x44 | Structure | Structure |
TM2 | 91 | N | 2.45x45 | Structure | Structure |
TM2 | 92 | L | 2.46x46 | Structure | Structure |
TM2 | 93 | A | 2.47x47 | Structure | Structure |
TM2 | 94 | V | 2.48x48 | Structure | Structure |
TM2 | 95 | A | 2.49x49 | Structure | Structure |
TM2 | 96 | D | 2.50x50 | Structure | Structure |
TM2 | 97 | L | 2.51x51 | Structure | Structure |
TM2 | 98 | L | 2.52x52 | Structure | Structure |
TM2 | 99 | V | 2.53x53 | Structure | Structure |
TM2 | 100 | N | 2.54x54 | Structure | Structure |
TM2 | 101 | T | 2.55x55 | Structure | Structure |
TM2 | 102 | L | 2.56x551 | Structure | Structure |
TM2 | 103 | C | 2.57x56 | Structure | Structure |
TM2 | 104 | L | 2.58x57 | Structure | Structure |
TM2 | 105 | P | 2.59x58 | Structure | Structure |
TM2 | 106 | F | 2.60x59 | Structure | Structure |
TM2 | 107 | T | 2.61x60 | Structure | Structure |
TM2 | 108 | L | 2.62x61 | Structure | Structure |
TM2 | 109 | T | 2.63x62 | Structure | Structure |
TM2 | 110 | Y | 2.64x63 | Structure | Structure |
TM2 | 111 | T | 2.65x64 | Structure | Structure |
TM2 | 112 | L | 2.66x65 | Structure | Structure |
TM2 | 113 | M | 2.67x66 | Structure | AF2 |
TM2 | 114 | G | 2.68x67 | Structure | Structure |
ECL1 | 115 | E | 23.49x49 | Structure | AF2 |
ECL1 | 116 | W | 23.50x50 | Structure | Structure |
ECL1 | 117 | K | 23.51x51 | Structure | AF2 |
ECL1 | 118 | M | 23.52x52 | Structure | AF2 |
TM3 | 119 | G | 3.21x21 | Structure | Structure |
TM3 | 120 | P | 3.22x22 | Structure | Structure |
TM3 | 121 | V | 3.23x23 | Structure | Structure |
TM3 | 122 | L | 3.24x24 | Structure | Structure |
TM3 | 123 | C | 3.25x25 | Structure | Structure |
TM3 | 124 | H | 3.26x26 | Structure | Structure |
TM3 | 125 | L | 3.27x27 | Structure | Structure |
TM3 | 126 | V | 3.28x28 | Structure | Structure |
TM3 | 127 | P | 3.29x29 | Structure | Structure |
TM3 | 128 | Y | 3.30x30 | Structure | Structure |
TM3 | 129 | A | 3.31x31 | Structure | Structure |
TM3 | 130 | Q | 3.32x32 | Structure | Structure |
TM3 | 131 | G | 3.33x33 | Structure | Structure |
TM3 | 132 | L | 3.34x34 | Structure | Structure |
TM3 | 133 | A | 3.35x35 | Structure | Structure |
TM3 | 134 | V | 3.36x36 | Structure | Structure |
TM3 | 135 | Q | 3.37x37 | Structure | Structure |
TM3 | 136 | V | 3.38x38 | Structure | Structure |
TM3 | 137 | S | 3.39x39 | Structure | Structure |
TM3 | 138 | T | 3.40x40 | Structure | Structure |
TM3 | 139 | I | 3.41x41 | Structure | Structure |
TM3 | 140 | T | 3.42x42 | Structure | Structure |
TM3 | 141 | L | 3.43x43 | Structure | Structure |
TM3 | 142 | T | 3.44x44 | Structure | Structure |
TM3 | 143 | V | 3.45x45 | Structure | Structure |
TM3 | 144 | I | 3.46x46 | Structure | Structure |
TM3 | 145 | A | 3.47x47 | Structure | Structure |
TM3 | 146 | L | 3.48x48 | Structure | Structure |
TM3 | 147 | D | 3.49x49 | Structure | Structure |
TM3 | 148 | R | 3.50x50 | Structure | Structure |
TM3 | 149 | H | 3.51x51 | Structure | Structure |
TM3 | 150 | R | 3.52x52 | Structure | Structure |
TM3 | 151 | C | 3.53x53 | Structure | Structure |
TM3 | 152 | I | 3.54x54 | Structure | Structure |
TM3 | 153 | V | 3.55x55 | Structure | Structure |
TM3 | 154 | Y | 3.56x56 | Structure | Structure |
ICL2 | 155 | H | - | Structure | Structure |
ICL2 | 156 | L | - | Structure | Structure |
ICL2 | 157 | E | - | Structure | Structure |
ICL2 | 158 | S | - | Structure | Structure |
ICL2 | 159 | K | - | Structure | Structure |
ICL2 | 160 | I | - | Structure | Structure |
TM4 | 161 | S | 4.38x38 | Structure | Structure |
TM4 | 162 | K | 4.39x39 | Structure | Structure |
TM4 | 163 | R | 4.40x40 | Structure | Structure |
TM4 | 164 | I | 4.41x41 | Structure | Structure |
TM4 | 165 | S | 4.42x42 | Structure | Structure |
TM4 | 166 | F | 4.43x43 | Structure | Structure |
TM4 | 167 | L | 4.44x44 | Structure | Structure |
TM4 | 168 | I | 4.45x45 | Structure | Structure |
TM4 | 169 | I | 4.46x46 | Structure | Structure |
TM4 | 170 | G | 4.47x47 | Structure | Structure |
TM4 | 171 | L | 4.48x48 | Structure | Structure |
TM4 | 172 | A | 4.49x49 | Structure | Structure |
TM4 | 173 | W | 4.50x50 | Structure | Structure |
TM4 | 174 | G | 4.51x51 | Structure | Structure |
TM4 | 175 | I | 4.52x52 | Structure | Structure |
TM4 | 176 | S | 4.53x53 | Structure | Structure |
TM4 | 177 | A | 4.54x54 | Structure | Structure |
TM4 | 178 | L | 4.55x55 | Structure | Structure |
TM4 | 179 | L | 4.56x56 | Structure | Structure |
TM4 | 180 | A | 4.57x57 | Structure | Structure |
TM4 | 181 | S | 4.58x59 | Structure | Structure |
TM4 | 182 | P | 4.59x60 | Structure | Structure |
TM4 | 183 | L | 4.60x61 | Structure | Structure |
TM4 | 184 | A | 4.61x62 | Structure | Structure |
TM4 | 185 | I | 4.62x63 | Structure | Structure |
TM4 | 186 | F | 4.63x64 | Structure | Structure |
TM4 | 187 | R | 4.64x65 | Structure | Structure |
ECL2 | 188 | E | - | Structure | Structure |
ECL2 | 189 | Y | - | Structure | Structure |
ECL2 | 190 | S | - | Structure | Structure |
ECL2 | 191 | L | - | Structure | Structure |
ECL2 | 192 | I | - | Structure | Structure |
ECL2 | 193 | E | - | Structure | AF2 |
ECL2 | 194 | I | - | Structure | Structure |
ECL2 | 195 | I | - | Structure | Structure |
ECL2 | 196 | P | - | Structure | Structure |
ECL2 | 197 | D | - | Structure | Structure |
ECL2 | 198 | F | - | Structure | Structure |
ECL2 | 199 | E | - | Structure | AF2 |
ECL2 | 200 | I | - | Structure | Structure |
ECL2 | 201 | V | - | Structure | Structure |
ECL2 | 202 | A | - | Structure | Structure |
ECL2 | 203 | C | 45.50x50 | Structure | Structure |
ECL2 | 204 | T | 45.51x51 | Structure | Structure |
ECL2 | 205 | E | 45.52x52 | Structure | Structure |
ECL2 | 206 | K | - | Structure | Structure |
ECL2 | 207 | W | - | Structure | Structure |
ECL2 | 208 | P | - | Structure | Structure |
ECL2 | 209 | G | - | Structure | Structure |
ECL2 | 210 | E | - | Structure | Structure |
ECL2 | 211 | E | - | Structure | Structure |
ECL2 | 212 | K | - | Structure | Structure |
TM5 | 213 | S | 5.32x33 | Structure | Structure |
TM5 | 214 | I | 5.33x34 | Structure | Structure |
TM5 | 215 | Y | 5.34x35 | Structure | Structure |
TM5 | 216 | G | 5.35x36 | Structure | Structure |
TM5 | 217 | T | 5.36x37 | Structure | Structure |
TM5 | 218 | V | 5.37x38 | Structure | Structure |
TM5 | 219 | Y | 5.38x39 | Structure | Structure |
TM5 | 220 | S | 5.39x40 | Structure | Structure |
TM5 | 221 | L | 5.40x41 | Structure | Structure |
TM5 | 222 | S | 5.41x42 | Structure | Structure |
TM5 | 223 | S | 5.42x43 | Structure | Structure |
TM5 | 224 | L | 5.43x44 | Structure | Structure |
TM5 | 225 | L | 5.44x45 | Structure | Structure |
TM5 | 226 | I | 5.45x46 | Structure | Structure |
TM5 | 227 | L | 5.46x461 | Structure | Structure |
TM5 | 228 | Y | 5.47x47 | Structure | Structure |
TM5 | 229 | V | 5.48x48 | Structure | Structure |
TM5 | 230 | L | 5.49x49 | Structure | Structure |
TM5 | 231 | P | 5.50x50 | Structure | Structure |
TM5 | 232 | L | 5.51x51 | Structure | Structure |
TM5 | 233 | G | 5.52x52 | Structure | Structure |
TM5 | 234 | I | 5.53x53 | Structure | Structure |
TM5 | 235 | I | 5.54x54 | Structure | Structure |
TM5 | 236 | S | 5.55x55 | Structure | Structure |
TM5 | 237 | F | 5.56x56 | Structure | Structure |
TM5 | 238 | S | 5.57x57 | Structure | Structure |
TM5 | 239 | Y | 5.58x58 | Structure | Structure |
TM5 | 240 | T | 5.59x59 | Structure | Structure |
TM5 | 241 | R | 5.60x60 | Structure | Structure |
TM5 | 242 | I | 5.61x61 | Structure | Structure |
TM5 | 243 | W | 5.62x62 | Structure | Structure |
TM5 | 244 | S | 5.63x63 | Structure | Structure |
TM5 | 245 | K | 5.64x64 | Structure | Structure |
TM5 | 246 | L | 5.65x65 | Structure | Structure |
TM5 | 247 | K | 5.66x66 | Structure | Structure |
TM5 | 248 | N | 5.67x67 | Structure | Structure |
TM5 | 249 | H | 5.68x68 | Structure | Structure |
TM5 | 250 | V | 5.69x69 | Structure | Structure |
TM5 | 251 | S | 5.70x70 | Structure | Structure |
TM5 | 252 | P | 5.71x71 | Structure | Structure |
TM5 | 253 | G | 5.72x72 | Structure | Structure |
ICL3 | 254 | A | - | Structure | Structure |
ICL3 | 255 | A | - | Structure | Structure |
TM6 | 256 | N | 6.23x23 | Structure | Structure |
TM6 | 257 | D | 6.24x24 | Structure | Structure |
TM6 | 258 | H | 6.25x25 | Structure | Structure |
TM6 | 259 | Y | 6.26x26 | Structure | Structure |
TM6 | 260 | H | 6.27x27 | Structure | Structure |
TM6 | 261 | Q | 6.28x28 | Structure | Structure |
TM6 | 262 | R | 6.29x29 | Structure | Structure |
TM6 | 263 | R | 6.30x30 | Structure | Structure |
TM6 | 264 | Q | 6.31x31 | Structure | Structure |
TM6 | 265 | K | 6.32x32 | Structure | Structure |
TM6 | 266 | T | 6.33x33 | Structure | Structure |
TM6 | 267 | T | 6.34x34 | Structure | Structure |
TM6 | 268 | K | 6.35x35 | Structure | Structure |
TM6 | 269 | M | 6.36x36 | Structure | Structure |
TM6 | 270 | L | 6.37x37 | Structure | Structure |
TM6 | 271 | V | 6.38x38 | Structure | Structure |
TM6 | 272 | C | 6.39x39 | Structure | Structure |
TM6 | 273 | V | 6.40x40 | Structure | Structure |
TM6 | 274 | V | 6.41x41 | Structure | Structure |
TM6 | 275 | V | 6.42x42 | Structure | Structure |
TM6 | 276 | V | 6.43x43 | Structure | Structure |
TM6 | 277 | F | 6.44x44 | Structure | Structure |
TM6 | 278 | A | 6.45x45 | Structure | Structure |
TM6 | 279 | V | 6.46x46 | Structure | Structure |
TM6 | 280 | S | 6.47x47 | Structure | Structure |
TM6 | 281 | W | 6.48x48 | Structure | Structure |
TM6 | 282 | L | 6.49x49 | Structure | Structure |
TM6 | 283 | P | 6.50x50 | Structure | Structure |
TM6 | 284 | L | 6.51x51 | Structure | Structure |
TM6 | 285 | H | 6.52x52 | Structure | Structure |
TM6 | 286 | A | 6.53x53 | Structure | Structure |
TM6 | 287 | F | 6.54x54 | Structure | Structure |
TM6 | 288 | Q | 6.55x55 | Structure | Structure |
TM6 | 289 | L | 6.56x56 | Structure | Structure |
TM6 | 290 | A | 6.57x57 | Structure | Structure |
TM6 | 291 | V | 6.58x58 | Structure | Structure |
TM6 | 292 | D | 6.59x59 | Structure | Structure |
TM6 | 293 | I | 6.60x60 | Structure | Structure |
TM6 | 294 | D | 6.61x61 | Structure | Structure |
ECL3 | 295 | S | - | Structure | Structure |
ECL3 | 296 | Q | - | Structure | Structure |
ECL3 | 297 | V | - | Structure | Structure |
ECL3 | 298 | L | - | Structure | Structure |
TM7 | 299 | D | 7.27x26 | Structure | Structure |
TM7 | 300 | L | 7.28x27 | Structure | Structure |
TM7 | 301 | K | 7.29x28 | Structure | Structure |
TM7 | 302 | E | 7.30x29 | Structure | Structure |
TM7 | 303 | Y | 7.31x30 | Structure | Structure |
TM7 | 304 | K | 7.32x31 | Structure | AF2 |
TM7 | 305 | L | 7.33x32 | Structure | Structure |
TM7 | 306 | I | 7.34x33 | Structure | Structure |
TM7 | 307 | F | 7.35x34 | Structure | Structure |
TM7 | 308 | T | 7.36x35 | Structure | Structure |
TM7 | 309 | V | 7.37x36 | Structure | Structure |
TM7 | 310 | F | 7.38x37 | Structure | Structure |
TM7 | 311 | H | 7.39x38 | Structure | Structure |
TM7 | 312 | I | 7.40x39 | Structure | Structure |
TM7 | 313 | I | 7.41x40 | Structure | Structure |
TM7 | 314 | A | 7.42x41 | Structure | Structure |
TM7 | 315 | M | 7.43x42 | Structure | Structure |
TM7 | 316 | C | 7.44x43 | Structure | Structure |
TM7 | 317 | S | 7.45x45 | Structure | Structure |
TM7 | 318 | T | 7.46x46 | Structure | Structure |
TM7 | 319 | F | 7.47x47 | Structure | Structure |
TM7 | 320 | A | 7.48x48 | Structure | Structure |
TM7 | 321 | N | 7.49x49 | Structure | Structure |
TM7 | 322 | P | 7.50x50 | Structure | Structure |
TM7 | 323 | L | 7.51x51 | Structure | Structure |
TM7 | 324 | L | 7.52x52 | Structure | Structure |
TM7 | 325 | Y | 7.53x53 | Structure | Structure |
TM7 | 326 | G | 7.54x54 | Structure | Structure |
TM7 | 327 | W | 7.55x55 | Structure | Structure |
TM7 | 328 | M | 7.56x56 | Structure | Structure |
H8 | 329 | N | 8.47x47 | Structure | Structure |
H8 | 330 | S | 8.48x48 | Structure | Structure |
H8 | 331 | N | 8.49x49 | Structure | Structure |
H8 | 332 | Y | 8.50x50 | Structure | Structure |
H8 | 333 | R | 8.51x51 | Structure | Structure |
H8 | 334 | K | 8.52x52 | Structure | Structure |
H8 | 335 | A | 8.53x53 | Structure | Structure |
H8 | 336 | F | 8.54x54 | Structure | Structure |
H8 | 337 | L | 8.55x55 | Structure | Structure |
H8 | 338 | S | 8.56x56 | Structure | Structure |
H8 | 339 | A | 8.57x57 | Structure | Structure |
H8 | 340 | F | 8.58x58 | Structure | Structure |
H8 | 341 | R | 8.59x59 | Structure | Structure |
H8 | 342 | C | 8.60x60 | AF2 | AF2 |
H8 | 343 | E | 8.61x61 | AF2 | AF2 |
H8 | 344 | Q | 8.62x62 | AF2 | AF2 |
H8 | 345 | R | 8.63x63 | AF2 | AF2 |
C-term | 346 | L | - | AF2 | AF2 |
C-term | 347 | D | - | AF2 | AF2 |
C-term | 348 | A | - | AF2 | AF2 |
C-term | 349 | I | - | AF2 | AF2 |
C-term | 350 | H | - | AF2 | AF2 |
C-term | 351 | S | - | AF2 | AF2 |
C-term | 352 | E | - | AF2 | AF2 |
C-term | 353 | V | - | AF2 | AF2 |
C-term | 354 | S | - | AF2 | AF2 |
C-term | 355 | V | - | AF2 | AF2 |
GPCR - G protein interface interactions
The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle
(Gα residues)
and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid,
hydrophobic - dashed,
ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.
GPCR-G protein backbone (bb) or sidechain (sc):
Structures
0 structures selected.
Sequence Color
Interaction frequency filter (%)
Gα,
Gβ,
Gγ,
GPCR
Interaction cut-off: strict (stick), loose (line)
Interaction type |
GPCR Segment |
AA |
Number |
Generic number |
Gα segment |
AA |
Number |
Generic number |
---|---|---|---|---|---|---|---|---|
Ionic | ICL2 | E | 157 | - | G.hns1 | R | 32 | G.hns1.03 |
Polar | ICL2 | E | 157 | - | G.hns1 | R | 32 | G.hns1.03 |
Hydrophobic | ICL2 | E | 157 | - | G.hns1 | R | 32 | G.hns1.03 |
Van-der-waals | ICL2 | E | 157 | - | G.hns1 | R | 32 | G.hns1.03 |
Hydrophobic | TM3 | R | 148 | 3x50 | G.H5 | L | 353 | G.H5.25 |
Van-der-waals | TM3 | R | 148 | 3x50 | G.H5 | L | 353 | G.H5.25 |
Polar | C-term | E | 352 | - | G.h2s4 | E | 216 | G.h2s4.02 |
Hydrophobic | C-term | E | 352 | - | G.h2s4 | E | 216 | G.h2s4.02 |
Van-der-waals | C-term | E | 352 | - | G.h2s4 | E | 216 | G.h2s4.02 |
Hydrophobic | ICL2 | H | 155 | - | G.H5 | I | 344 | G.H5.16 |
Van-der-waals | ICL2 | H | 155 | - | G.H5 | I | 344 | G.H5.16 |
Hydrophobic | TM5 | P | 252 | 5x71 | G.H5 | F | 334 | G.H5.06 |
Van-der-waals | TM5 | P | 252 | 5x71 | G.H5 | F | 334 | G.H5.06 |
Polar | C-term | S | 351 | - | G.H3 | F | 259 | G.H3.18 |
Hydrophobic | TM6 | M | 269 | 6x36 | G.H5 | L | 353 | G.H5.25 |
Polar | C-term | V | 355 | - | G.H3 | W | 258 | G.H3.17 |
Hydrophobic | C-term | V | 355 | - | G.H3 | W | 258 | G.H3.17 |
Van-der-waals | C-term | V | 355 | - | G.H3 | W | 258 | G.H3.17 |
Hydrophobic | TM5 | P | 252 | 5x71 | G.H5 | D | 337 | G.H5.09 |
Van-der-waals | TM5 | P | 252 | 5x71 | G.H5 | D | 337 | G.H5.09 |
Hydrophobic | TM5 | L | 246 | 5x65 | G.H5 | I | 344 | G.H5.16 |
Ionic | TM5 | H | 249 | 5x68 | G.H5 | D | 341 | G.H5.13 |
Polar | TM5 | H | 249 | 5x68 | G.H5 | D | 341 | G.H5.13 |
Hydrophobic | TM5 | H | 249 | 5x68 | G.H5 | D | 341 | G.H5.13 |
Van-der-waals | TM5 | H | 249 | 5x68 | G.H5 | D | 341 | G.H5.13 |
Polar | TM3 | R | 148 | 3x50 | G.H5 | C | 351 | G.H5.23 |
Hydrophobic | TM3 | R | 148 | 3x50 | G.H5 | C | 351 | G.H5.23 |
Polar | TM6 | N | 256 | 6x23 | G.H5 | K | 345 | G.H5.17 |
Polar | C-term | S | 351 | - | G.H3 | K | 257 | G.H3.16 |
Hydrophobic | C-term | S | 351 | - | G.H3 | K | 257 | G.H3.16 |
Van-der-waals | C-term | S | 351 | - | G.H3 | K | 257 | G.H3.16 |
Polar | C-term | S | 354 | - | G.H3 | W | 258 | G.H3.17 |
Hydrophobic | C-term | S | 354 | - | G.H3 | W | 258 | G.H3.17 |
Van-der-waals | C-term | S | 354 | - | G.H3 | W | 258 | G.H3.17 |
Polar | C-term | S | 351 | - | G.H3 | W | 258 | G.H3.17 |
Hydrophobic | C-term | S | 351 | - | G.H3 | W | 258 | G.H3.17 |
Van-der-waals | C-term | S | 351 | - | G.H3 | W | 258 | G.H3.17 |
Polar | TM6 | R | 262 | 6x29 | G.H5 | F | 354 | G.H5.26 |
Aromatic | TM6 | R | 262 | 6x29 | G.H5 | F | 354 | G.H5.26 |
Hydrophobic | TM6 | R | 262 | 6x29 | G.H5 | F | 354 | G.H5.26 |
Van-der-waals | TM6 | R | 262 | 6x29 | G.H5 | F | 354 | G.H5.26 |
Hydrophobic | C-term | S | 354 | - | G.H3 | K | 257 | G.H3.16 |
Hydrophobic | ICL2 | H | 155 | - | G.H5 | I | 343 | G.H5.15 |
Van-der-waals | ICL2 | H | 155 | - | G.H5 | I | 343 | G.H5.15 |
Hydrophobic | TM5 | L | 246 | 5x65 | G.H5 | L | 348 | G.H5.20 |
Hydrophobic | TM2 | T | 85 | 2x39 | G.H5 | C | 351 | G.H5.23 |
Van-der-waals | TM2 | T | 85 | 2x39 | G.H5 | C | 351 | G.H5.23 |
Hydrophobic | TM3 | I | 152 | 3x54 | G.H5 | I | 344 | G.H5.16 |
Van-der-waals | TM3 | I | 152 | 3x54 | G.H5 | I | 344 | G.H5.16 |
Van-der-waals | TM6 | T | 266 | 6x33 | G.H5 | F | 354 | G.H5.26 |
Polar | TM6 | T | 266 | 6x33 | G.H5 | L | 353 | G.H5.25 |
Hydrophobic | TM6 | T | 266 | 6x33 | G.H5 | L | 353 | G.H5.25 |
Van-der-waals | TM6 | T | 266 | 6x33 | G.H5 | L | 353 | G.H5.25 |
Polar | H8 | N | 331 | 8x49 | G.H5 | D | 350 | G.H5.22 |
Hydrophobic | H8 | N | 331 | 8x49 | G.H5 | D | 350 | G.H5.22 |
Van-der-waals | H8 | N | 331 | 8x49 | G.H5 | D | 350 | G.H5.22 |
Hydrophobic | TM5 | H | 249 | 5x68 | G.H5 | T | 340 | G.H5.12 |
Van-der-waals | TM7 | M | 328 | 7x56 | G.H5 | G | 352 | G.H5.24 |
Hydrophobic | C-term | V | 355 | - | G.H2 | H | 213 | G.H2.09 |
Van-der-waals | C-term | V | 355 | - | G.H2 | H | 213 | G.H2.09 |
Polar | C-term | E | 352 | - | G.h2s4 | G | 217 | G.h2s4.03 |
Hydrophobic | C-term | E | 352 | - | G.h2s4 | G | 217 | G.h2s4.03 |
Polar | ICL2 | S | 158 | - | G.hns1 | R | 32 | G.hns1.03 |
Hydrophobic | ICL3 | A | 254 | - | G.S6 | Y | 320 | G.S6.02 |
Hydrophobic | C-term | S | 351 | - | G.h2s4 | E | 216 | G.h2s4.02 |
Van-der-waals | C-term | S | 351 | - | G.h2s4 | E | 216 | G.h2s4.02 |
Polar | C-term | S | 351 | - | G.h3s5 | T | 260 | G.h3s5.01 |
Hydrophobic | C-term | S | 351 | - | G.h3s5 | T | 260 | G.h3s5.01 |
Van-der-waals | C-term | S | 351 | - | G.h3s5 | T | 260 | G.h3s5.01 |
Hydrophobic | TM3 | I | 152 | 3x54 | G.H5 | N | 347 | G.H5.19 |
Van-der-waals | TM3 | I | 152 | 3x54 | G.H5 | N | 347 | G.H5.19 |
Polar | TM6 | N | 256 | 6x23 | G.h4s6 | E | 318 | G.h4s6.12 |
Hydrophobic | TM6 | N | 256 | 6x23 | G.h4s6 | E | 318 | G.h4s6.12 |
Van-der-waals | TM6 | N | 256 | 6x23 | G.h4s6 | E | 318 | G.h4s6.12 |
Hydrophobic | TM3 | I | 152 | 3x54 | G.H5 | L | 348 | G.H5.20 |
Van-der-waals | TM3 | I | 152 | 3x54 | G.H5 | L | 348 | G.H5.20 |
Ionic | TM6 | H | 258 | 6x25 | G.h4s6 | E | 318 | G.h4s6.12 |
Polar | TM6 | H | 258 | 6x25 | G.h4s6 | E | 318 | G.h4s6.12 |
Polar | TM3 | C | 151 | 3x53 | G.H5 | N | 347 | G.H5.19 |
Hydrophobic | TM3 | C | 151 | 3x53 | G.H5 | N | 347 | G.H5.19 |
Van-der-waals | TM3 | C | 151 | 3x53 | G.H5 | N | 347 | G.H5.19 |
Hydrophobic | ICL3 | A | 255 | - | G.H4 | E | 308 | G.H4.16 |
Van-der-waals | ICL3 | A | 255 | - | G.H4 | E | 308 | G.H4.16 |
Van-der-waals | TM5 | G | 253 | 5x72 | G.S6 | T | 321 | G.S6.03 |
Hydrophobic | C-term | V | 355 | - | G.h2s4 | E | 216 | G.h2s4.02 |
Van-der-waals | C-term | V | 355 | - | G.h2s4 | E | 216 | G.h2s4.02 |
Polar | TM6 | N | 256 | 6x23 | G.H5 | D | 341 | G.H5.13 |
Polar | TM3 | C | 151 | 3x53 | G.H5 | C | 351 | G.H5.23 |
Hydrophobic | TM3 | C | 151 | 3x53 | G.H5 | C | 351 | G.H5.23 |
Van-der-waals | TM3 | C | 151 | 3x53 | G.H5 | C | 351 | G.H5.23 |
Polar | H8 | N | 329 | 8x47 | G.H5 | G | 352 | G.H5.24 |
Hydrophobic | H8 | N | 329 | 8x47 | G.H5 | G | 352 | G.H5.24 |
Van-der-waals | H8 | N | 329 | 8x47 | G.H5 | G | 352 | G.H5.24 |
Polar | H8 | S | 330 | 8x48 | G.H5 | F | 354 | G.H5.26 |
Van-der-waals | H8 | S | 330 | 8x48 | G.H5 | F | 354 | G.H5.26 |
Van-der-waals | ICL2 | H | 155 | - | G.H5 | N | 347 | G.H5.19 |
Polar | H8 | N | 331 | 8x49 | G.H5 | K | 349 | G.H5.21 |
Van-der-waals | H8 | N | 331 | 8x49 | G.H5 | K | 349 | G.H5.21 |
Polar | H8 | N | 329 | 8x47 | G.H5 | C | 351 | G.H5.23 |
Hydrophobic | H8 | N | 329 | 8x47 | G.H5 | C | 351 | G.H5.23 |
Van-der-waals | H8 | N | 329 | 8x47 | G.H5 | C | 351 | G.H5.23 |
Polar | ICL2 | S | 158 | - | G.hns1 | A | 31 | G.hns1.02 |