CHEMBL28833


SMILES CCCc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1
InChIKey QRQZDZPCRVUFNL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 334.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.17 8.17 8.17 ChEMBL
D3 DRD3 Rat Dopamine A pKi 6.04 6.04 6.04 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.15 6.15 6.15 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.19 5.19 5.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database