Ligand Data

Ligand

id 100277
Name CHEMBL284912
SMILES CCCN(CCCCN1CCOCC1)C1COc2cccc(OC)c2C1
InChIKey LUDDDWQEQCANFX-UHFFFAOYSA-N
Type small-molecule
External Links

Structure

Properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight 362.3


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
5-HT2A 5HT2A Bovine 5-Hydroxytryptamine A (Rhodopsin) 10000 10000 10000
α2A ADA2A Bovine Adrenoceptors A (Rhodopsin) 4000 4000 4000
α1A ADA1A Bovine Adrenoceptors A (Rhodopsin) 10000 10000 10000
D1 DRD1 Bovine Dopamine A (Rhodopsin) 100000 100000 100000
D2 DRD2 Bovine Dopamine A (Rhodopsin) 30.0 30.0 30.0
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A (Rhodopsin) 4.0 6.0 8.0