CHEMBL246438


SMILES COC1(c2ccc(Cl)cc2)CCN(Cc2c[nH]c3ccccc23)CC1
InChIKey KEFPLNQTZDBPPV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 354.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.47 7.47 7.47 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.58 6.58 6.58 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.17 7.17 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 6.61 6.61 6.61 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.46 7.46 7.46 ChEMBL