CHEMBL294459


SMILES N#CC(C#N)=Cc1cc(CN2CCN(c3ccccc3)CC2)c[nH]1
InChIKey FASYQPOSAUOTDU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 317.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.14 5.14 5.14 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.41 8.41 8.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.63 5.63 5.63 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.73 5.87 6.01 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database