ractopamine
| SMILES | CC(NCC(c1ccc(cc1)O)O)CCc1ccc(cc1)O |
| InChIKey | YJQZYXCXBBCEAQ-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 4 |
| Hydrogen bond donors | 4 |
| Rotatable bonds | 7 |
| Molecular weight (Da) | 301.2 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| β2 | ADRB2 | Human | Adrenoceptors | A | pKi | 6.6 | 6.75 | 6.9 | Guide to Pharmacology |
| β2 | ADRB2 | Human | Adrenoceptors | A | pKi | 6.75 | 6.75 | 6.75 | ChEMBL |
| β2 | ADRB2 | Human | Adrenoceptors | A | pKi | 6.74 | 6.74 | 6.74 | PDSP Ki database |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| β2 | ADRB2 | Human | Adrenoceptors | A | pEC50 | 7.6 | 7.7 | 7.8 | Guide to Pharmacology |
| TA1 | TAAR1 | Mouse | Trace amine | A | pEC50 | 4.8 | 4.8 | 4.8 | Guide to Pharmacology |
| β2 | ADRB2 | Guinea pig | Adrenoceptors | A | pEC50 | 8.21 | 8.21 | 8.21 | ChEMBL |
| β2 | ADRB2 | Human | Adrenoceptors | A | pIC50 | 6.48 | 6.48 | 6.48 | ChEMBL |