CHEMBL296953


SMILES O=C(NCN1CCN(c2ccccc2Cl)CC1)c1ccc(Cl)cc1
InChIKey QXXSJVZBKIQIJR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 363.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.08 8.21 8.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.18 7.18 7.18 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.3 6.74 7.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.08 8.08 8.08 ChEMBL