Ro64-6198


SMILES O=C1NCN(C21CCN(CC2)[C@H]1CC[C@H]2c3c1cccc3CCC2)c1ccccc1
InChIKey JLFMYEAXZNPWBK-REWPJTCUSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 401.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.41 9.41 9.41 Guide to Pharmacology
NOP OPRX Human Opioid A pKi 8.95 8.95 8.95 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.41 7.41 7.41 Guide to Pharmacology
NOP OPRX Human Opioid A pEC50 7.68 7.68 7.68 ChEMBL