CHEMBL300553


SMILES N#CC(C#N)=Cc1[nH]ccc1CN1CCN(c2ccc(Cl)cc2)CC1
InChIKey RCACIEKJQOIDQV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 351.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.87 4.87 4.87 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.9 6.9 6.9 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.12 5.12 5.12 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.82 4.94 5.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database