RP-52770


SMILES Clc1cccc(c1)NC(=O)c1ccn2c1CSC2c1cccnc1
InChIKey MJGVBIXLFIUPQU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 355.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pKi 8.2 8.2 8.2 Guide to Pharmacology
PAF PTAFR Human Platelet-activating factor A pKd 8.4 8.4 8.4 Guide to Pharmacology
PAF PTAFR Guinea pig Platelet-activating factor A pKi 6.56 6.56 6.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database