CHEMBL302000


SMILES O=C1Cc2c(OCCNCc3ccc(Cl)cc3)ccc(Cl)c2N1
InChIKey JPSMZWRPAFVXDX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 350.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 8.39 8.62 8.85 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.72 5.72 5.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database