FENDILINE


SMILES CC(NCCC(c1ccccc1)c1ccccc1)c1ccccc1
InChIKey NMKSAYKQLCHXDK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 315.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.49 5.49 5.49 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.26 8.26 8.26 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CaS CASR Human Calcium-sensing C pEC50 6.0 6.0 6.0 ChEMBL
GPR55 GPR55 Human GPR18, GPR55 and GPR119 A pIC50 5.51 5.51 5.51 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 5.0 5.0 5.0 ChEMBL
CaS CASR Human Calcium-sensing C pEC50 8.22 8.22 8.22 Drug Central
CaS CASR Bovine Calcium-sensing C pEC50 8.31 8.31 8.31 Drug Central