CHEMBL3040164


SMILES Cc1ccc2c3c1-c1c(ccc(O)c1O)C[C@H]3N(C)CC2
InChIKey HRCGTLOWYKJDFC-CYBMUJFWSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 281.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.73 6.73 6.73 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.64 7.64 7.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.27 7.27 7.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pEC50 7.66 7.66 7.66 ChEMBL
D2 DRD2 Human Dopamine A pEC50 8.29 8.29 8.29 ChEMBL