CHEMBL1161424


SMILES Cc1cc(O)cc(C)c1C[C@H](N)[C@@H](O)C/C=C/[C@H](O)[C@@H](Cc1ccccc1)C(=O)OCCc1ccccc1
InChIKey FWZKNXOQDVISEU-JKROCSJBSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 13
Molecular weight (Da) 517.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 6.58 6.58 6.58 ChEMBL
δ OPRD Human Opioid A pKi 7.25 7.25 7.25 ChEMBL
μ OPRM Human Opioid A pKi 9.62 9.62 9.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pEC50 8.38 8.38 8.38 ChEMBL