CHEMBL305975


SMILES COc1ccccc1NC(=O)Nc1nc(-c2ccccn2)nc2ccccc12
InChIKey GCKZXLFIXXZGHV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 371.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A1 AA1R Rat Adenosine A pKi 4.07 4.07 4.07 ChEMBL
A3 AA3R Human Adenosine A pKi 4.55 6.47 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A3 AA3R Human Adenosine A pIC50 8.1 8.1 8.1 ChEMBL