CHEMBL26188


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccccc2)CC1
InChIKey JYOIFSSKXBNYGV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 367.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.77 6.77 6.77 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.89 7.5 8.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.89 6.97 7.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 6.81 6.81 6.81 ChEMBL