secretin
| SMILES | None |
| InChIKey | KKNIUBFRGPFELP-UHFFFAOYSA-N |
| Sequence | HSDGTFTSELSRLRDSARLQRLLQGLV |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Endogenous |
| Approved drug | Yes |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| secretin | SCTR | Rat | Glucagon | B1 | pKi | 8.0 | 8.5 | 9.0 | Guide to Pharmacology |
| VPAC1 | VIPR1 | Human | VIP and PACAP | B1 | pKi | 5.0 | 5.0 | 5.0 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| secretin | SCTR | Human | Glucagon | B1 | pEC50 | 9.7 | 9.7 | 9.7 | Guide to Pharmacology |
| VPAC2 | VIPR2 | Human | VIP and PACAP | B1 | pIC50 | 5.3 | 5.3 | 5.3 | Guide to Pharmacology |
| PAC1 | PACR | Rat | VIP and PACAP | B1 | pIC50 | 4.5 | 4.5 | 4.5 | Guide to Pharmacology |
| VPAC1 | VIPR1 | Rat | VIP and PACAP | B1 | pIC50 | 6.5 | 6.5 | 6.5 | Guide to Pharmacology |
| VPAC2 | VIPR2 | Rat | VIP and PACAP | B1 | pIC50 | 4.5 | 4.5 | 4.5 | Guide to Pharmacology |
| secretin | SCTR | Rat | Glucagon | B1 | pIC50 | 9.0 | 9.0 | 9.0 | Guide to Pharmacology |
| VPAC1 | VIPR1 | Human | VIP and PACAP | B1 | pIC50 | 5.8 | 5.8 | 5.8 | Guide to Pharmacology |