CHEMBL26426


SMILES COc1ccccc1N1CCN(CCNC(=O)C2CCCc3c(OC)cccc32)CC1
InChIKey CPGVFFIAFKTJQY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 423.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.82 6.82 6.82 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.66 7.66 7.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 6.35 6.35 6.35 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 7.46 7.46 7.46 ChEMBL