SR16835


SMILES O=C1Cc2c(N1C1CCN(CC1)C1CCC3c4c1cccc4CCC3)cccc2
InChIKey SZKWDIATUVLAAW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 6.17 6.17 6.17 Guide to Pharmacology
μ OPRM Human Opioid A pKi 7.1 7.1 7.1 Guide to Pharmacology
NOP OPRX Human Opioid A pKi 7.94 7.94 7.94 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.34 7.34 7.34 Guide to Pharmacology