SRIF-14
SMILES | None |
InChIKey | VVEJUSYNERNRME-XGFVQVCISA-N |
Sequence | AGCKNFFWKTFTSC |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Endogenous |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
SST1 | SSR1 | Human | Somatostatin | A | pKi | 8.6 | 9.05 | 9.5 | Guide to Pharmacology |
SST2 | SSR2 | Human | Somatostatin | A | pKi | 8.9 | 9.7 | 10.5 | Guide to Pharmacology |
SST3 | SSR3 | Human | Somatostatin | A | pKi | 8.7 | 9.35 | 10.0 | Guide to Pharmacology |
SST4 | SSR4 | Human | Somatostatin | A | pKi | 8.4 | 8.85 | 9.3 | Guide to Pharmacology |
SST5 | SSR5 | Human | Somatostatin | A | pKi | 8.4 | 9.15 | 9.9 | Guide to Pharmacology |
SST5 | SSR5 | Rat | Somatostatin | A | pKi | 8.4 | 8.4 | 8.4 | Guide to Pharmacology |
SST2 | SSR2 | Rat | Somatostatin | A | pKi | 8.8 | 8.8 | 8.8 | Guide to Pharmacology |
SST5 | SSR5 | Mouse | Somatostatin | A | pKi | 7.7 | 8.4 | 9.1 | Guide to Pharmacology |
SST3 | SSR3 | Rat | Somatostatin | A | pKi | 8.9 | 8.9 | 8.9 | Guide to Pharmacology |
SST2 | SSR2 | Mouse | Somatostatin | A | pKi | 8.8 | 9.2 | 9.6 | Guide to Pharmacology |
SST4 | SSR4 | Human | Somatostatin | A | pKd | 9.7 | 9.7 | 9.7 | ChEMBL |
SST5 | SSR5 | Human | Somatostatin | A | pKd | 9.49 | 9.49 | 9.49 | ChEMBL |
SST1 | SSR1 | Human | Somatostatin | A | pKd | 9.54 | 9.54 | 9.54 | ChEMBL |
SST3 | SSR3 | Human | Somatostatin | A | pKd | 10.49 | 10.49 | 10.49 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
SST2 | SSR2 | Rat | Somatostatin | A | pEC50 | 8.99 | 9.07 | 9.14 | Guide to Pharmacology |
SST3 | SSR3 | Mouse | Somatostatin | A | pIC50 | 10.1 | 10.1 | 10.1 | Guide to Pharmacology |
SST1 | SSR1 | Rat | Somatostatin | A | pIC50 | 8.4 | 8.4 | 8.4 | Guide to Pharmacology |
SST4 | SSR4 | Rat | Somatostatin | A | pIC50 | 8.2 | 8.2 | 8.2 | Guide to Pharmacology |