Chembl3125990


SMILES CCCN(CCN1CCN(c2ccc(-c3cccc(O)c3)cc2)CC1)[C@H]1CCc2nc(N)sc2C1
InChIKey VITUDJAVASFPKN-DEOSSOPVSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 491.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.76 8.76 8.76 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.43 6.43 6.43 ChEMBL
D3 DRD3 Human Dopamine A pEC50 10.0 10.0 10.0 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.8 7.8 7.8 ChEMBL