CHEMBL27811


SMILES C1=C(c2c[nH]c3ccccc23)CCNC1
InChIKey CIRSPTXGPFAXRE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 198.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.72 6.76 6.85 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.2 6.37 6.53 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.7 6.7 6.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 8.43 8.43 8.43 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 6.85 6.85 6.85 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 6.79 6.79 6.79 ChEMBL