CHEMBL313620


SMILES COc1ccccc1N1CCN(CCCOc2ccc(-c3nc4ccccc4[nH]3)cc2)CC1
InChIKey WWABSSMRPUCUEJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 442.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 7.79 7.79 7.79 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.77 8.77 8.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.06 8.06 8.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database