TRH
SMILES | None |
InChIKey | XNSAINXGIQZQOO-SRVKXCTJSA-N |
Sequence | XHP |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Endogenous |
Approved drug | Yes |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
TRH1 | TRHR | Rat | Thyrotropin-releasing hormone | A | pKi | 7.37 | 7.54 | 7.7 | ChEMBL |
TRH1 | TRFR | Human | Thyrotropin-releasing hormone | A | pKi | 7.7 | 7.7 | 7.7 | ChEMBL |
TRH1 | TRFR | Human | Thyrotropin-releasing hormone | A | pKi | 8.11 | 8.11 | 8.11 | Drug Central |
TRH1 | TRHR | Mouse | Thyrotropin-releasing hormone | A | pKi | 8.1 | 8.1 | 8.1 | Drug Central |
motilin | Q9R297 | Rat | Motilin | A | pKi | 8.1 | 8.1 | 8.1 | Drug Central |
TRH1 | TRHR | Mouse | Thyrotropin-releasing hormone | A | pKi | 7.64 | 7.82 | 8.0 | ChEMBL |
TRH1 | TRHR | Rat | Thyrotropin-releasing hormone | A | pKi | 8.11 | 8.11 | 8.11 | Drug Central |
TRH1 | TRHR | Rat | Thyrotropin-releasing hormone | A | pKi | 7.4 | 7.4 | 7.4 | Guide to Pharmacology |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
TRH1 | TRHR | Rat | Thyrotropin-releasing hormone | A | pEC50 | 8.52 | 8.52 | 8.52 | ChEMBL |
TRH1 | TRFR | Human | Thyrotropin-releasing hormone | A | pEC50 | 8.52 | 8.52 | 8.52 | ChEMBL |
TRH1 | TRHR | Mouse | Thyrotropin-releasing hormone | A | pEC50 | 8.49 | 8.99 | 9.31 | ChEMBL |
TRH1 | TRHR | Mouse | Thyrotropin-releasing hormone | A | pIC50 | 7.58 | 8.09 | 8.59 | ChEMBL |