Chembl316983


SMILES CCCN(CCC)[C@H]1CCn2c(C=O)ccc2C1
InChIKey RIOOLQVLOZQLQJ-ZDUSSCGKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 248.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.58 4.58 4.58 ChEMBL
D2 DRD2 Bovine Dopamine A pKi 5.19 6.64 7.68 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.6 6.55 7.5 ChEMBL
D4 DRD4 Human Dopamine A pEC50 5.38 5.38 5.38 ChEMBL
D2 DRD2 Rat Dopamine A pEC50 7.1 7.53 7.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.82 7.65 8.28 ChEMBL
D3 DRD3 Human Dopamine A pEC50 8.96 8.96 8.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.16 6.34 7.39 ChEMBL