CHEMBL28607


SMILES COc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1
InChIKey NNGCXJPRHBHODU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 322.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.44 8.44 8.44 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.89 8.89 8.89 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.41 5.41 5.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database