Chembl318606

Chemical Properties

SMILES CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N(CCC(=O)N[C@@H]1CCCCNC1=O)Cc1ccc(Cl)c(Cl)c1
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight 626.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey KKLMRJSMWOEEFA-OAQYLSRUSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK2 NK2R Human Tachykinin A pIC50 8.26 8.26 8.26 ChEMBL
NK1 NK1R Human Tachykinin A pIC50 8.85 8.85 8.85 ChEMBL