CHEMBL288096


SMILES CCCN1CCc2cc(O)cc3c2[C@H]1Cc1ccc(O)c(O)c1-3
InChIKey HLRBSTGXOFUEHW-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 311.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 6.04 6.04 6.04 ChEMBL
D2 DRD2 Rat Dopamine A pKi 10.28 10.28 10.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 5.76 5.76 5.76 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.85 6.52 8.2 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 9.49 9.82 10.15 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 5.0 5.0 5.0 ChEMBL