CHEMBL29067


SMILES CCOC(=O)C1=C(c2ccc(-n3c(C)nc4cnccc43)cc2)NC(C)=C(C(=O)Nc2ccccn2)C1c1ccccc1Cl
InChIKey ODRYSCQFUGFOSU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 604.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Guinea pig Platelet-activating factor A pKi 8.15 8.23 8.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Guinea pig Platelet-activating factor A pIC50 8.37 8.37 8.37 ChEMBL
PAF PTAFR Human Platelet-activating factor A pIC50 7.5 8.1 8.7 ChEMBL