CHEMBL1171002
SMILES | O=C(c1ccc(Oc2cccc(Cl)c2)nc1)N1CCCN(C2CCC2)CC1 |
InChIKey | HWQIIVFZLJEVAL-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 0 |
Rotatable bonds | 4 |
Molecular weight (Da) | 385.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H3 | HRH3 | Rat | Histamine | A | pKd | 8.3 | 8.3 | 8.3 | ChEMBL |
H3 | HRH3 | Rat | Histamine | A | pKi | 7.82 | 7.82 | 7.82 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKi | 9.0 | 9.0 | 9.0 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKd | 9.06 | 9.06 | 9.06 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |