CHEMBL317333


SMILES N#CCCN1CCC(c2cn(-c3ccc(F)cc3)c3ccc(-c4ncccn4)cc23)CC1
InChIKey ALBWWALSEOWKRA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Golden hamster Adrenoceptors A pKi 8.34 8.34 8.34 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pKi 8.41 8.41 8.41 ChEMBL
D1 DRD1 Rat Dopamine A pKi 5.52 5.52 5.52 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.31 6.31 6.31 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.16 5.16 5.16 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.17 6.17 6.17 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.17 7.17 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database