CHEMBL292418


SMILES Oc1cc2c(cc1Cl)CCNCC2c1ccccc1
InChIKey ZVKJSJAERRMBMR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 273.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 8.63 8.63 8.63 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.17 6.17 6.17 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.31 8.31 8.31 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.86 5.86 5.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pEC50 7.39 7.39 7.39 ChEMBL