CHEMBL294458


SMILES N#CC(C#N)=Cc1cc(CN2CCN(c3ccc(Cl)cc3)CC2)c[nH]1
InChIKey LGXAESURRIWEJV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 351.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.28 5.28 5.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.16 5.16 5.16 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.99 5.06 5.13 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.24 8.24 8.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database