VU0155041


SMILES O=C([C@H]1CCCC[C@H]1C(=O)O)Nc1cc(Cl)cc(c1)Cl
InChIKey VSMUYYFJVFSVCA-NWDGAFQWSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 315.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations mGlu4

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu4 GRM4 Human Metabotropic glutamate C pEC50 6.1 6.1 6.1 Guide to Pharmacology
mGlu4 GRM4 Human Metabotropic glutamate C pEC50 6.12 6.12 6.13 ChEMBL