CHEMBL1171886


SMILES O=C(c1ccc(Oc2ccc(Cl)cc2)nc1)N1CCCN(C2CCC2)CC1
InChIKey AHYIQKYLWZRVTE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 385.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKd 8.4 8.4 8.4 ChEMBL
H3 HRH3 Rat Histamine A pKi 7.64 7.64 7.64 ChEMBL
H3 HRH3 Human Histamine A pKd 9.22 9.22 9.22 ChEMBL
H3 HRH3 Human Histamine A pKi 7.23 7.23 7.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database