CHEMBL297827


SMILES C(=C/c1ccccc1)\C[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1
InChIKey RCLSMBSYDRCUSB-CEBMEMTBSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 296.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.99 6.99 6.99 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.07 7.07 7.07 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 8.7 8.7 8.7 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 7.15 7.15 7.15 ChEMBL