WAY-207024


SMILES CC(c1ccc(cc1)c1[nH]c2c(n1)cccc2N1CCN(CC1)Cc1ccc2c(c1)nccn2)(C)C
InChIKey AVEVJMZJJJDOCI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 476.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pKi 6.07 6.07 6.07 ChEMBL
NK2 NK2R Human Tachykinin A pKi 6.48 6.48 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pIC50 7.92 7.92 7.92 Guide to Pharmacology
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pIC50 7.15 7.15 7.15 Guide to Pharmacology
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pIC50 6.44 6.81 7.15 ChEMBL
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pIC50 7.55 7.73 7.92 ChEMBL