CHEMBL320572
SMILES | O=C1CC(CN2CCC(c3noc4cc(F)ccc34)CC2)Cc2sccc21 |
InChIKey | UUWNMTNBWJAYKN-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 0 |
Rotatable bonds | 3 |
Molecular weight (Da) | 384.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT2B | 5HT2B | Rat | 5-Hydroxytryptamine | A | pKd | 6.24 | 6.24 | 6.24 | ChEMBL |
D1 | DRD1 | Rat | Dopamine | A | pKi | 6.89 | 6.89 | 6.89 | ChEMBL |
D2 | DRD2 | Rat | Dopamine | A | pKi | 7.26 | 7.26 | 7.26 | ChEMBL |
5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pKi | 6.69 | 6.79 | 6.95 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |