CHEMBL322802


SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C
InChIKey XNUNIHJOMFCFRQ-LIRRHRJNSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 387.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 5.66 6.68 7.7 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.33 7.25 8.13 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.46 7.79 8.13 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 4.72 4.94 5.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database